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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [41]
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- Validations
- Western blot [5]
- Immunohistochemistry [1]
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- Product number
- ABIN152911 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD36 Molecule (thrombospondin Receptor) (CD36) (AA 100-200) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Bovine, Porcine, Simian
- Host
- Rabbit
- Epitope
- AA 100-200
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Do not freeze.
Submitted references LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro.
mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects.
Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase.
Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.
Hepatic Overexpression of CD36 Improves Glycogen Homeostasis and Attenuates High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance.
Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation.
New evidence for the role of ceramide in the development of hepatic insulin resistance.
Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.
PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation.
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration.
Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions.
The excreted polysaccharide of Pleurotus eryngii inhibits the foam-cell formation via down-regulation of CD36.
Thrombospondin-1 triggers macrophage IL-10 production and promotes resolution of experimental lung injury.
Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.
Thyroid hormone reverses aging-induced myocardial fatty acid oxidation defects and improves the response to acutely increased afterload.
Extracorporeal membrane oxygenation promotes long chain fatty acid oxidation in the immature swine heart in vivo.
Investigation of the factors associated with circulating soluble CD36 levels in patients with HCV-related chronic liver disease.
Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice.
Stored platelets alter glycerophospholipid and sphingolipid species, which are differentially transferred to newly released extracellular vesicles.
Macrophage gene expression and foam cell formation are regulated by plasminogen.
Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling.
C-Myc induced compensated cardiac hypertrophy increases free fatty acid utilization for the citric acid cycle.
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
CD36 mediates proximal tubular binding and uptake of albumin and is upregulated in proteinuric nephropathies.
Chronic exposure to rifaximin causes hepatic steatosis in pregnane X receptor-humanized mice.
Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction.
CD9 tetraspanin interacts with CD36 on the surface of macrophages: a possible regulatory influence on uptake of oxidized low density lipoprotein.
Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke.
Hyperinsulinemia and ectopic fat deposition can develop in the face of hyperadiponectinemia in young obese rats.
Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.
Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo.
SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells.
A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis.
Selection of an antibody library identifies a pathway to induce immunity by targeting CD36 on steady-state CD8 alpha+ dendritic cells.
IL-6 deficiency increases fatty acid transporters and intramuscular lipid content in red but not white skeletal muscle.
Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J
eLife 2017 Nov 16;6
eLife 2017 Nov 16;6
Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro.
Lavie L, Dyugovskaya L, Polyakov A, Rogovoy O, Leder E
Journal of visualized experiments : JoVE 2017 Jan 25;(119)
Journal of visualized experiments : JoVE 2017 Jan 25;(119)
mTORC2 Promotes Tumorigenesis via Lipid Synthesis.
Guri Y, Colombi M, Dazert E, Hindupur SK, Roszik J, Moes S, Jenoe P, Heim MH, Riezman I, Riezman H, Hall MN
Cancer cell 2017 Dec 11;32(6):807-823.e12
Cancer cell 2017 Dec 11;32(6):807-823.e12
Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects.
Chen X, Austin ED, Talati M, Fessel JP, Farber-Eger EH, Brittain EL, Hemnes AR, Loyd JE, West J
The European respiratory journal 2017 Aug;50(2)
The European respiratory journal 2017 Aug;50(2)
Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase.
Chen Y, Huang W, Yang M, Xin G, Cui W, Xie Z, Silverstein RL
Arteriosclerosis, thrombosis, and vascular biology 2017 Aug;37(8):1462-1469
Arteriosclerosis, thrombosis, and vascular biology 2017 Aug;37(8):1462-1469
Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Sachdev V, Leopold C, Bauer R, Patankar JV, Iqbal J, Obrowsky S, Boverhof R, Doktorova M, Scheicher B, Goeritzer M, Kolb D, Turnbull AV, Zimmer A, Hoefler G, Hussain MM, Groen AK, Kratky D
Biochimica et biophysica acta 2016 Sep;1861(9 Pt A):1132-1141
Biochimica et biophysica acta 2016 Sep;1861(9 Pt A):1132-1141
Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.
Vaillant F, Lauzier B, Ruiz M, Shi Y, Lachance D, Rivard ME, Bolduc V, Thorin E, Tardif JC, Des Rosiers C
American journal of physiology. Heart and circulatory physiology 2016 Oct 1;311(4):H991-H1003
American journal of physiology. Heart and circulatory physiology 2016 Oct 1;311(4):H991-H1003
Hepatic Overexpression of CD36 Improves Glycogen Homeostasis and Attenuates High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance.
Garbacz WG, Lu P, Miller TM, Poloyac SM, Eyre NS, Mayrhofer G, Xu M, Ren S, Xie W
Molecular and cellular biology 2016 Nov 1;36(21):2715-2727
Molecular and cellular biology 2016 Nov 1;36(21):2715-2727
Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.
Salameh A, Daquinag AC, Staquicini DI, An Z, Hajjar KA, Pasqualini R, Arap W, Kolonin MG
JCI insight 2016 Jul 7;1(10)
JCI insight 2016 Jul 7;1(10)
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation.
Souza AC, Bocharov AV, Baranova IN, Vishnyakova TG, Huang YG, Wilkins KJ, Hu X, Street JM, Alvarez-Prats A, Mullick AE, Patterson AP, Remaley AT, Eggerman TL, Yuen PS, Star RA
Kidney international 2016 Apr;89(4):809-22
Kidney international 2016 Apr;89(4):809-22
New evidence for the role of ceramide in the development of hepatic insulin resistance.
Konstantynowicz-Nowicka K, Harasim E, Baranowski M, Chabowski A
PloS one 2015;10(1):e0116858
PloS one 2015;10(1):e0116858
Altered metabolism of LDL in the arterial wall precedes atherosclerosis regression.
Bartels ED, Christoffersen C, Lindholm MW, Nielsen LB
Circulation research 2015 Nov 6;117(11):933-42
Circulation research 2015 Nov 6;117(11):933-42
PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation.
Barroso E, Rodríguez-Rodríguez R, Chacón MR, Maymó-Masip E, Ferrer L, Salvadó L, Salmerón E, Wabistch M, Palomer X, Vendrell J, Wahli W, Vázquez-Carrera M
Biochimica et biophysica acta 2015 May;1852(5):1049-58
Biochimica et biophysica acta 2015 May;1852(5):1049-58
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice.
Zidek LM, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, Leutz A, Sonenberg N, Wang ZQ, von Maltzahn J, Müller C, Calkhoven CF
EMBO reports 2015 Aug;16(8):1022-36
EMBO reports 2015 Aug;16(8):1022-36
Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration.
Ye R, Holland WL, Gordillo R, Wang M, Wang QA, Shao M, Morley TS, Gupta RK, Stahl A, Scherer PE
eLife 2014 Oct 23;3
eLife 2014 Oct 23;3
Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions.
Srikanthan S, Li W, Silverstein RL, McIntyre TM
Journal of thrombosis and haemostasis : JTH 2014 Nov;12(11):1906-17
Journal of thrombosis and haemostasis : JTH 2014 Nov;12(11):1906-17
The excreted polysaccharide of Pleurotus eryngii inhibits the foam-cell formation via down-regulation of CD36.
Chen J, Yong Y, Xia X, Wang Z, Liang Y, Zhang S, Lu L
Carbohydrate polymers 2014 Nov 4;112:16-23
Carbohydrate polymers 2014 Nov 4;112:16-23
Thrombospondin-1 triggers macrophage IL-10 production and promotes resolution of experimental lung injury.
Zhao Y, Xiong Z, Lechner EJ, Klenotic PA, Hamburg BJ, Hulver M, Khare A, Oriss T, Mangalmurti N, Chan Y, Zhang Y, Ross MA, Stolz DB, Rosengart MR, Pilewski J, Ray P, Ray A, Silverstein RL, Lee JS
Mucosal immunology 2014 Mar;7(2):440-8
Mucosal immunology 2014 Mar;7(2):440-8
Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.
Khan S, Abu Jawdeh BG, Goel M, Schilling WP, Parker MD, Puchowicz MA, Yadav SP, Harris RC, El-Meanawy A, Hoshi M, Shinlapawittayatorn K, Deschênes I, Ficker E, Schelling JR
The Journal of clinical investigation 2014 Mar;124(3):1057-68
The Journal of clinical investigation 2014 Mar;124(3):1057-68
Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.
Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, Silverstein RL, Gladson CL, DiDonato JA, Brown JM, McIntyre T, Hazen SL, Horbinski C, Rich JN, Lathia JD
Stem cells (Dayton, Ohio) 2014 Jul;32(7):1746-58
Stem cells (Dayton, Ohio) 2014 Jul;32(7):1746-58
Thyroid hormone reverses aging-induced myocardial fatty acid oxidation defects and improves the response to acutely increased afterload.
Ledee D, Portman MA, Kajimoto M, Isern N, Olson AK
PloS one 2013;8(6):e65532
PloS one 2013;8(6):e65532
Extracorporeal membrane oxygenation promotes long chain fatty acid oxidation in the immature swine heart in vivo.
Kajimoto M, O'Kelly Priddy CM, Ledee DR, Xu C, Isern N, Olson AK, Portman MA
Journal of molecular and cellular cardiology 2013 Sep;62:144-52
Journal of molecular and cellular cardiology 2013 Sep;62:144-52
Investigation of the factors associated with circulating soluble CD36 levels in patients with HCV-related chronic liver disease.
Himoto T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Kurokohchi K, Inukai M, Masugata H, Goda F, Senda S, Haba R, Ueno M, Yamaoka G, Masaki T
Diabetology & metabolic syndrome 2013 Sep 9;5(1):51
Diabetology & metabolic syndrome 2013 Sep 9;5(1):51
Long-term exposure to a high-fat diet results in the development of glucose intolerance and insulin resistance in interleukin-1 receptor I-deficient mice.
McGillicuddy FC, Reynolds CM, Finucane O, Coleman E, Harford KA, Grant C, Sergi D, Williams LM, Mills KH, Roche HM
American journal of physiology. Endocrinology and metabolism 2013 Oct 1;305(7):E834-44
American journal of physiology. Endocrinology and metabolism 2013 Oct 1;305(7):E834-44
Stored platelets alter glycerophospholipid and sphingolipid species, which are differentially transferred to newly released extracellular vesicles.
Pienimaeki-Roemer A, Ruebsaamen K, Boettcher A, Orsó E, Scherer M, Liebisch G, Kilalic D, Ahrens N, Schmitz G
Transfusion 2013 Mar;53(3):612-26
Transfusion 2013 Mar;53(3):612-26
Macrophage gene expression and foam cell formation are regulated by plasminogen.
Das R, Ganapathy S, Mahabeleshwar GH, Drumm C, Febbraio M, Jain MK, Plow EF
Circulation 2013 Mar 19;127(11):1209-18, e1-16
Circulation 2013 Mar 19;127(11):1209-18, e1-16
Enhanced recovery from ischemia-reperfusion injury in PI3Kα dominant negative hearts: investigating the role of alternate PI3K isoforms, increased glucose oxidation and MAPK signaling.
McLean BA, Kienesberger PC, Wang W, Masson G, Zhabyeyev P, Dyck JR, Oudit GY
Journal of molecular and cellular cardiology 2013 Jan;54:9-18
Journal of molecular and cellular cardiology 2013 Jan;54:9-18
C-Myc induced compensated cardiac hypertrophy increases free fatty acid utilization for the citric acid cycle.
Olson AK, Ledee D, Iwamoto K, Kajimoto M, O'Kelly Priddy C, Isern N, Portman MA
Journal of molecular and cellular cardiology 2013 Feb;55:156-64
Journal of molecular and cellular cardiology 2013 Feb;55:156-64
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
Khan OM, Akula MK, Skålen K, Karlsson C, Ståhlman M, Young SG, Borén J, Bergo MO
Circulation 2013 Feb 19;127(7):782-90
Circulation 2013 Feb 19;127(7):782-90
CD36 mediates proximal tubular binding and uptake of albumin and is upregulated in proteinuric nephropathies.
Baines RJ, Chana RS, Hall M, Febbraio M, Kennedy D, Brunskill NJ
American journal of physiology. Renal physiology 2012 Oct;303(7):F1006-14
American journal of physiology. Renal physiology 2012 Oct;303(7):F1006-14
Chronic exposure to rifaximin causes hepatic steatosis in pregnane X receptor-humanized mice.
Cheng J, Krausz KW, Tanaka N, Gonzalez FJ
Toxicological sciences : an official journal of the Society of Toxicology 2012 Oct;129(2):456-68
Toxicological sciences : an official journal of the Society of Toxicology 2012 Oct;129(2):456-68
Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction.
Kienesberger PC, Pulinilkunnil T, Sung MM, Nagendran J, Haemmerle G, Kershaw EE, Young ME, Light PE, Oudit GY, Zechner R, Dyck JR
Molecular and cellular biology 2012 Feb;32(4):740-50
Molecular and cellular biology 2012 Feb;32(4):740-50
CD9 tetraspanin interacts with CD36 on the surface of macrophages: a possible regulatory influence on uptake of oxidized low density lipoprotein.
Huang W, Febbraio M, Silverstein RL
PloS one 2011;6(12):e29092
PloS one 2011;6(12):e29092
Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke.
Faustino JV, Wang X, Johnson CE, Klibanov A, Derugin N, Wendland MF, Vexler ZS
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Sep 7;31(36):12992-3001
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Sep 7;31(36):12992-3001
Hyperinsulinemia and ectopic fat deposition can develop in the face of hyperadiponectinemia in young obese rats.
Marecki JC, Ronis MJ, Shankar K, Badger TM
The Journal of nutritional biochemistry 2011 Feb;22(2):142-52
The Journal of nutritional biochemistry 2011 Feb;22(2):142-52
Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.
Sos BC, Harris C, Nordstrom SM, Tran JL, Balázs M, Caplazi P, Febbraio M, Applegate MA, Wagner KU, Weiss EJ
The Journal of clinical investigation 2011 Apr;121(4):1412-23
The Journal of clinical investigation 2011 Apr;121(4):1412-23
Scavenger receptors are associated with cellular interactions of S100A12 in vitro and in vivo.
Hoppmann S, Steinbach J, Pietzsch J
The international journal of biochemistry & cell biology 2010 May;42(5):651-61
The international journal of biochemistry & cell biology 2010 May;42(5):651-61
SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells.
Truong TQ, Aubin D, Falstrault L, Brodeur MR, Brissette L
Cell biochemistry and function 2010 Aug;28(6):480-9
Cell biochemistry and function 2010 Aug;28(6):480-9
A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis.
Lee JH, Wada T, Febbraio M, He J, Matsubara T, Lee MJ, Gonzalez FJ, Xie W
Gastroenterology 2010 Aug;139(2):653-63
Gastroenterology 2010 Aug;139(2):653-63
Selection of an antibody library identifies a pathway to induce immunity by targeting CD36 on steady-state CD8 alpha+ dendritic cells.
Tagliani E, Guermonprez P, Sepúlveda J, López-Bravo M, Ardavín C, Amigorena S, Benvenuti F, Burrone OR
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3201-9
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3201-9
IL-6 deficiency increases fatty acid transporters and intramuscular lipid content in red but not white skeletal muscle.
Chabowski A, Zmijewska M, Gorski J, Bonen A, Kaminski K, Kozuch M, Winnicka MM
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008 Dec;59 Suppl 7:105-17
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008 Dec;59 Suppl 7:105-17
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Supportive validation
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