DPABH-07065

antibody from Creative Diagnostics

Targeting: IRF9 ISGF3G

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-07065

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-07065, RRID:AB_2502804

Product name

Rabbit Anti-Human IRF9 Polyclonal antibody

Antibody type

Polyclonal

Description

Interferon regulatory factor 9 (IRF9) also named Interferon-stimulated gene factor 3 gamma (ISGF3) is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL