COA8

This gene encodes a protein that localizes to the mitochondria, where it stimulates the release of cytochrome c, thereby promoting programmed cell death. Mutations in this gene have been found in individuals with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Description

cytochrome c oxidase assembly factor 8

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

14:q32.33 (103562962 - 103607523)

Ensembl ID

ENSG00000256053  (ver. 99.38)

Orthologs

Mouse Apopt1: ENSMUSG00000037787

UniProt

Q96IL0

neXtProt

NX_Q96IL0

Human splice variants
Mouse splice variants