Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx015919 - Provider product page
- Provider
- Abbexa
- Product name
- Forkhead Box Protein P2 (FOXP2) Antibody
- Antibody type
- Monoclonal
- Description
- This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors.It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut.The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes.This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development.Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia.Multiple alternative transcripts encoding different isoforms have been identified in this gene.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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