abx015919

antibody from Abbexa

Targeting: FOXP2 CAGH44, SPCH1, TNRC10

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx015919

Provider

Abbexa

Product name

Forkhead Box Protein P2 (FOXP2) Antibody

Antibody type

Monoclonal

Description

This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors.It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut.The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes.This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development.Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia.Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.