AMM02466G

antibody from Leading Biology

Targeting: USP14 TGT

Western blot (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM02466G

Provider

Leading Biology

Product name

USP14 Antibody (N-term)

Antibody type

Monoclonal

Description

Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

889CT6.2.1

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.