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- Product number
- ABIN393858 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ubiquitin Specific Peptidase 14 (USP14) (AA 395-495) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Epitope
- AA 395-495
- Isotype
- IgG
- Antibody clone number
- 6D6
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references New genetic associations detected in a host response study to hepatitis B vaccine.
The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions.
Defining the human deubiquitinating enzyme interaction landscape.
Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation.
USP14 inhibits ER-associated degradation via interaction with IRE1alpha.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity 2010 Apr;11(3):232-8
Genes and immunity 2010 Apr;11(3):232-8
The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions.
Chen PC, Qin LN, Li XM, Walters BJ, Wilson JA, Mei L, Wilson SM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Sep 2;29(35):10909-19
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Sep 2;29(35):10909-19
Defining the human deubiquitinating enzyme interaction landscape.
Sowa ME, Bennett EJ, Gygi SP, Harper JW
Cell 2009 Jul 23;138(2):389-403
Cell 2009 Jul 23;138(2):389-403
Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation.
Mines MA, Goodwin JS, Limbird LE, Cui FF, Fan GH
The Journal of biological chemistry 2009 Feb 27;284(9):5742-52
The Journal of biological chemistry 2009 Feb 27;284(9):5742-52
USP14 inhibits ER-associated degradation via interaction with IRE1alpha.
Nagai A, Kadowaki H, Maruyama T, Takeda K, Nishitoh H, Ichijo H
Biochemical and biophysical research communications 2009 Feb 20;379(4):995-1000
Biochemical and biophysical research communications 2009 Feb 20;379(4):995-1000
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Supportive validation
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