H2AC21

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

Description

H2A clustered histone 21

Tissue specificity

Tissue enriched (brain)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (149887469 - 149887965)

Ensembl ID

ENSG00000184270  (ver. 103.38)

Orthologs

Mouse H2ac21: ENSMUSG00000063689

UniProt

Q8IUE6

neXtProt

NX_Q8IUE6

Human splice variants
Mouse splice variants

Protein structure