TAC4

This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Tachykinin precursor 4

Tissue specificity

Tissue enhanced (pituitary gland)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

17 (49838309 - 49848017)

Ensembl ID

ENSG00000176358  (ver. 103.38)

Orthologs

Mouse Tac4: ENSMUSG00000020872

UniProt

Q86UU9

neXtProt

NX_Q86UU9

Human splice variants
Mouse splice variants

Protein structure