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Protein structure
IRAK4
Interleukin 1 receptor associated kinase 4NY-REN-64
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Invitrogen Antibodies |  700026 |
2 references | Monoclonal |
WB
ICC
IHC
FC
ChIP
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| antibodies-online | ABIN969218 |
2 references | Monoclonal |
WB
EL
IHC
FC
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| Novus Biologicals | NBP2-37575 |
Monoclonal |
WB
EL
IP
IHC
FC
|
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| Proteintech Group | 18221-1-AP |
2 references | Polyclonal |
WB
EL
IP
IHC
|
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| OriGene | AM06659SU-N |
Monoclonal |
WB
EL
IHC
FC
|
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