CABT-B10011

COL25A1 antibody from Creative Diagnostics
Western blot
Recommended by provider
ELISA
Recommended by provider

Antibody data

Product number
CABT-B10011
Provider
Creative Diagnostics
Product name
Mouse anti-Human COL25A1 monoclonal antibody, clone 2E3
Provider product page
Creative Diagnostics - CABT-B10011
Antibody type
Monoclonal
Description
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
2.00E+03
Vial size
100 _g
Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Provider Type Product Number
- No reagents -