11-3023-25

antibody from ABEOMICS Inc.
Targeting: TXNIP ARRDC6, EST01027, HHCPA78, THIF, VDUP1
Provider product page for 11-3023-25

Antibody data

Product number
11-3023-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-TxNIP/VDUP1 Antibody
Antibody type
Polyclonal
Description
TXNIP (thioredoxin interacting protein) inhibits thioredoxin activity by limiting its bioavailability in response to oxidative stress. TXNIP restores COPS5-induced suppression of CDKN1B stability by interacting with COPS5 and blocks the COPS5-mediated translocation of CDKN1B from nucleus to the cytoplasm. TXNIP functions as a transcriptional repressor. TXNIP has been reported to be a suppressor of tumor cell growth and inhibits the proteasomal degradation of DDIT4, contributing to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). TXNIP is expresed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdale.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant TxNIP
protein (amino acids 50-300) was us
ed as the immunogen for this antibo
dy.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
TXNIP protein structure - 11-3023-25 shown in red.