19972-1-AP

antibody from Proteintech Group

Targeting: MKI67 MIB-1, PPP1R105

Provider product page for 19972-1-AP

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [35]
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Product number: 19972-1-AP - Provider product page
Provider: Proteintech Group
Product name: KI67 antibody
Antibody type: Polyclonal
Description: KI67 antibody (Cat. #19972-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MKI67 protein structure - 19972-1-AP shown in red.

Submitted references FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development.

Kelel M, Yang RB, Tsai TF, Liang PH, Wu FY, Huang YT, Yang MF, Hsiao YP, Wang LF, Tu CF, Liu FT, Lee YL
The Journal of investigative dermatology 2021 Mar;141(3):512-522

PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.

Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506

6-Gingerol induces cell-cycle G1-phase arrest through AKT-GSK 3β-cyclin D1 pathway in renal-cell carcinoma.

Xu S, Zhang H, Liu T, Yang W, Lv W, He D, Guo P, Li L
Cancer chemotherapy and pharmacology 2020 Feb;85(2):379-390

Upregulation of oxidative stress-responsive 1(OXSR1) predicts poor prognosis and promotes hepatocellular carcinoma progression.

Chen J, Zhou J, Fu H, Ni X, Shan Y
Bioengineered 2020 Dec;11(1):958-971

Stathmin guides personalized therapy in oral squamous cell carcinoma.

Ju WT, Ma HL, Zhao TC, Liang SY, Zhu DW, Wang LZ, Li J, Zhang ZY, Zhou G, Zhong LP
Cancer science 2020 Apr;111(4):1303-1313

Identification of a small-molecule compound that inhibits homodimerization of oncogenic NAC1 protein and sensitizes cancer cells to anticancer agents.

Wang X, Ji C, Zhang H, Shan Y, Ren Y, Hu Y, Shi L, Guo L, Zhu W, Xia Y, Liu B, Rong Z, Wu B, Ming Z, Ren X, Song J, Yang J, Zhang Y
The Journal of biological chemistry 2019 Jun 21;294(25):10006-10017

The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.

Wang X, Fang H, Cheng Y, Li L, Sun X, Fu T, Huang P, Zhang A, Feng Z, Li C, Huang X, Li G, Du P, Yang H, Fang X, Li F, Gao Q, Liu B
Carcinogenesis 2018 May 3;39(5):708-718

Triptolide inhibits vascular endothelial growth factor-mediated angiogenesis in human breast cancer cells.

Liu H, Tang L, Li X, Li H
Experimental and therapeutic medicine 2018 Aug;16(2):830-836

TBL1XR1 predicts isolated tumor cells and micrometastasis in patients with TNM stage I/II colorectal cancer.

Liu H, Liu Z, Li K, Li S, Song L, Gong Z, Shi W, Yang H, Xu Y, Ning S, Ismail S, Chen Y
Journal of gastroenterology and hepatology 2017 Sep;32(9):1570-1580

Systematic evaluation of multifunctional paclitaxel-loaded polymeric mixed micelles as a potential anticancer remedy to overcome multidrug resistance.

Zhang J, Zhao X, Chen Q, Yin X, Xin X, Li K, Qiao M, Hu H, Chen D, Zhao X
Acta biomaterialia 2017 Mar 1;50:381-395

Renal cell carcinoma with synchronous ipsilateral urothelial carcinoma of the renal pelvis.

Lu Q, Zhuang J, Guo H
Oncology letters 2017 Jun;13(6):4521-4525

Circular RNA 0000096 affects cell growth and migration in gastric cancer.

Li P, Chen H, Chen S, Mo X, Li T, Xiao B, Yu R, Guo J
British journal of cancer 2017 Feb 28;116(5):626-633

Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation.

Li S, Yang LJ, Wang P, He YJ, Huang JM, Liu HW, Shen XF, Wang F
Food & nutrition research 2016;60:31288

Is Overexpression of Ki-67 a Prognostic Biomarker of Upper Tract Urinary Carcinoma? A Retrospective Cohort Study and Meta-Analysis.

Fan B, Zhang H, Jin H, Gai Y, Wang H, Zong H, Jin M, Yang H, Wan S, Zhu J, Xu S, Wang J, Yang D, Song X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(6):1613-1625

Deficiency of 53BP1 inhibits the radiosensitivity of colorectal cancer.

Xiao Y, Zheng X, Huang A, Liu T, Zhang T, Ma H
International journal of oncology 2016 Oct;49(4):1600-8

Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.

Ye J, Yao Y, Song Q, Li S, Hu Z, Yu Y, Hu C, Da X, Li H, Chen Q, Wang QK
Scientific reports 2016 Oct 4;6:34034

miR-320a regulates cell proliferation and apoptosis in multiple myeloma by targeting pre-B-cell leukemia transcription factor 3.

Lu Y, Wu D, Wang J, Li Y, Chai X, Kang Q
Biochemical and biophysical research communications 2016 May 13;473(4):1315-1320

Hepatitis B virus X protein up-regulates C4b-binding protein α through activating transcription factor Sp1 in protection of hepatoma cells from complement attack.

Feng G, Li J, Zheng M, Yang Z, Liu Y, Zhang S, Ye L, Zhang W, Zhang X
Oncotarget 2016 May 10;7(19):28013-26

miR-130b targets NKD2 and regulates the Wnt signaling to promote proliferation and inhibit apoptosis in osteosarcoma cells.

Li Z, Li Y, Wang N, Yang L, Zhao W, Zeng X
Biochemical and biophysical research communications 2016 Mar 18;471(4):479-85

Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.

Li X, Song Y, Zhang P, Zhu H, Chen L, Xiao Y, Xing Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613

Activation of liver X receptor inhibits the development of pulmonary carcinomas induced by 3-methylcholanthrene and butylated hydroxytoluene in BALB/c mice.

Wang Q, Sun L, Yang X, Ma X, Li Q, Chen Y, Liu Y, Zhang D, Li X, Xiang R, Wei Y, Han J, Duan Y
Scientific reports 2016 Jun 2;6:27295

Mitogen-inducible gene-6 partly mediates the inhibitory effects of prenatal dexamethasone exposure on endochondral ossification in long bones of fetal rats.

Zhang X, Shang-Guan Y, Ma J, Hu H, Wang L, Magdalou J, Chen L, Wang H
British journal of pharmacology 2016 Jul;173(14):2250-62

miR-16 targets fibroblast growth factor 2 to inhibit NPC cell proliferation and invasion via PI3K/AKT and MAPK signaling pathways.

He Q, Ren X, Chen J, Li Y, Tang X, Wen X, Yang X, Zhang J, Wang Y, Ma J, Liu N
Oncotarget 2016 Jan 19;7(3):3047-58

miR-186 inhibits cell proliferation in multiple myeloma by repressing Jagged1.

Liu Z, Zhang G, Yu W, Gao N, Peng J
Biochemical and biophysical research communications 2016 Jan 15;469(3):692-7

mTOR/P70S6K promotes spermatogonia proliferation and spermatogenesis in Sprague Dawley rats.

Xu H, Shen L, Chen X, Ding Y, He J, Zhu J, Wang Y, Liu X
Reproductive biomedicine online 2016 Feb;32(2):207-17

Intrauterine low-functional programming of IGF1 by prenatal nicotine exposure mediates the susceptibility to osteoarthritis in female adult rat offspring.

Tie K, Zhang X, Tan Y, Deng Y, Li J, Ni Q, Wang H, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Feb;30(2):785-97

CHIP promotes thyroid cancer proliferation via activation of the MAPK and AKT pathways.

Zhang L, Liu L, He X, Shen Y, Liu X, Wei J, Yu F, Tian J
Biochemical and biophysical research communications 2016 Aug 26;477(3):356-62

Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway.

Li X, Wang S, Zhu R, Li H, Han Q, Zhao RC
Journal of hematology & oncology 2016 Apr 18;9:42

MiR-129-3p promotes docetaxel resistance of breast cancer cells via CP110 inhibition.

Zhang Y, Wang Y, Wei Y, Li M, Yu S, Ye M, Zhang H, Chen S, Liu W, Zhang J
Scientific reports 2015 Oct 21;5:15424

Quercetin reverses experimental pulmonary arterial hypertension by modulating the TrkA pathway.

He Y, Cao X, Liu X, Li X, Xu Y, Liu J, Shi J
Experimental cell research 2015 Nov 15;339(1):122-34

Decreased Warburg effect induced by ATP citrate lyase suppression inhibits tumor growth in pancreatic cancer.

Zong H, Zhang Y, You Y, Cai T, Wang Y
Medical oncology (Northwood, London, England) 2015 Mar;32(3):85

Inhibition of tumor growth by U0126 is associated with induction of interferon-γ production.

Ma X, Wang Q, Liu Y, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao RQ, Duan Y, Han J
International journal of cancer 2015 Feb 15;136(4):771-83

Combining CXCL10 gene therapy and radiotherapy improved therapeutic efficacy in cervical cancer HeLa cell xenograft tumor models.

Zhao M, Ma Q, Xu J, Fu S, Chen L, Wang B, Wu J, Yang L
Oncology letters 2015 Aug;10(2):768-772

Spondin 1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma.

Chang H, Dong T, Ma X, Zhang T, Chen Z, Yang Z, Zhang Y
Biochemical and biophysical research communications 2015 Aug 14;464(1):45-50

CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.

Fei F, Li X, Xu L, Li D, Zhang Z, Guo X, Yang H, Chen Z, Xing J
Annals of surgical oncology 2014 Dec;21(13):4359-68

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