SON

This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Description

SON DNA binding protein

Protein family

Disease related genes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

21:q22.11 (33543038 - 33577481)

Ensembl ID

ENSG00000159140  (ver. 99.38)

Orthologs

Mouse Son: ENSMUSG00000022961

UniProt

P18583

neXtProt

NX_P18583

Human splice variants
Mouse splice variants