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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [273]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [7]
- Immunohistochemistry [4]
- Other assay [13]
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- Product number
- 40-2200 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- ZO-1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- 40-2200 was used successfully in the immunofluorescence analysis of Zo-1 in MDCK cells.
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.25 mg/mL
- Storage
- -20°C
Submitted references RGMa Participates in the Blood-Brain Barrier Dysfunction Through BMP/BMPR/YAP Signaling in Multiple Sclerosis.
Effect of heated tobacco products and traditional cigarettes on pulmonary toxicity and SARS-CoV-2-induced lung injury.
Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium.
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome.
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier.
Circular RNA circ-FoxO3 attenuates blood-brain barrier damage by inducing autophagy during ischemia/reperfusion.
Cell-Fibronectin Interactions and Actomyosin Contractility Regulate the Segmentation Clock and Spatio-Temporal Somite Cleft Formation during Chick Embryo Somitogenesis.
DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction.
Effects of intermittent hypoxia with thrombin in an in vitro model of human brain endothelial cells and their impact on PAR-1/PAR-3 cleavage.
A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups.
Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors.
The interplay between SARS-CoV-2 infected airway epithelium and immune cells modulates regulatory/inflammatory signals.
Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells.
Food-Derived High Arginine Peptides Promote Spermatogenesis Recovery in Busulfan Treated Mice.
Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.
The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.
Longitudinal [(18)F]FDG and [(13)N]NH(3) PET/CT imaging of brain and spinal cord in a canine hemisection spinal cord injury model.
ID4 Is Required for Normal Ependymal Cell Development.
Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages.
Role of miRNA-671-5p in Mediating Wnt/β-Catenin-Triggered Podocyte Injury.
Endothelial Thioredoxin-Interacting Protein Depletion Reduces Hemorrhagic Transformation in Hyperglycemic Mice after Embolic Stroke and Thrombolytic Therapy.
Multi-level inhibition of coronavirus replication by chemical ER stress.
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption.
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.
B6 Mouse Strain: The Best Fit for LPS-Induced Interstitial Cystitis Model.
Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids.
miR-200c-3p Regulates Epitelial-to-Mesenchymal Transition in Epicardial Mesothelial Cells by Targeting Epicardial Follistatin-Related Protein 1.
Functional model of rat thyroid follicles cultured in Matrigel.
The anesthetic sevoflurane induces tau trafficking from neurons to microglia.
Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells.
Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues.
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.
A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications.
A Novel Vasoactive Peptide "PG1" from Buffalo Ice-Cream Protects from Angiotensin-Evoked High Blood Pressure.
APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer's mice via cyclophilin A independently of amyloid-β.
Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers.
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration.
Molecular Mechanism of Stimulation of Na-K-ATPase by Leukotriene D4 in Intestinal Epithelial Cells.
Epithelial Regeneration in Human Corneas Preserved in an Active Storage Machine.
In vitro Measurement of Membrane Attack Complex in RPE Cells.
Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries.
Lactobacillus casei and Epidermal Growth Factor Prevent Osmotic Stress-Induced Tight Junction Disruption in Caco-2 Cell Monolayers.
Low-Intensity Extracorporeal Shock Wave Therapy Promotes Bladder Regeneration and Improves Overactive Bladder Induced by Ovarian Hormone Deficiency from Rat Animal Model to Human Clinical Trial.
Diammonium glycyrrhizinate lipid ligand ameliorates lipopolysaccharide-induced acute lung injury by modulating vascular endothelial barrier function.
Real-Time Monitoring the Effect of Cytopathic Hypoxia on Retinal Pigment Epithelial Barrier Functionality Using Electric Cell-Substrate Impedance Sensing (ECIS) Biosensor Technology.
Imaging the Cell Morphological Response to 3D Topography and Curvature in Engineered Intestinal Tissues.
Site-specific opening of the blood-brain barrier by extracellular histones.
Protocol for Differentiation of Human iPSCs into Pulmonary Neuroendocrine Cells.
Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice.
Treatment with interleukin-33 is non-toxic and protects retinal pigment epithelium in an ageing model of outer retinal degeneration.
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function.
Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD.
D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration.
Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells.
Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance.
EGF and a GSK3 Inhibitor Deplete Junctional E-cadherin and Stimulate Proliferation in the Mature Mammalian Ear.
Protective effect of emodin on intestinal epithelial tight junction barrier integrity in rats with sepsis induced by cecal ligation and puncture.
TIMP1 preserves the blood-brain barrier through interacting with CD63/integrin β 1 complex and regulating downstream FAK/RhoA signaling.
Hedgehog Signaling Regulates Epithelial Morphogenesis to Position the Ventral Embryonic Midline.
Astrocyte-derived VEGF increases cerebral microvascular permeability under high salt conditions.
Anisakis simplex products impair intestinal epithelial barrier function and occludin and zonula occludens-1 localisation in differentiated Caco-2 cells.
Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform.
Targeting QKI-7 in vivo restores endothelial cell function in diabetes.
S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling.
Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis.
Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation.
Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration.
Actin-Binding Protein Cortactin Promotes Pathogenesis of Experimental Autoimmune Encephalomyelitis by Supporting Leukocyte Infiltration into the Central Nervous System.
Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.
YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.
Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung's disease.
Syncytia formation by SARS-CoV-2-infected cells.
An organoid model to assay the role of CFTR in the human epididymis epithelium.
Soy Protein Nanofiber Scaffolds for Uniform Maturation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.
Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.
Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells.
Human Fallopian Tube Epithelial Cell Culture Model To Study Host Responses to Chlamydia trachomatis Infection.
Interaction of Staphylococcus aureus and Host Cells upon Infection of Bronchial Epithelium during Different Stages of Regeneration.
The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study.
HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells.
The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition.
Metformin Improves Fertility in Obese Males by Alleviating Oxidative Stress-Induced Blood-Testis Barrier Damage.
Lactobacillus fermentum species ameliorate dextran sulfate sodium-induced colitis by regulating the immune response and altering gut microbiota.
Poly-ε-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation.
Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.
Hepatic progenitor cell activation is induced by the depletion of the gut microbiome in mice.
Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.
BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration.
Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies.
Fusarium Mycotoxins Disrupt the Barrier and Induce IL-6 Release in a Human Placental Epithelium Cell Line.
Nanoparticle induced barrier function assessment at liquid-liquid and air-liquid interface in novel human lung epithelia cell lines.
Foxc2 is essential for podocyte function.
Organoid-derived C-Kit(+)/SSEA4(-) human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents.
Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins.
Dengue virus-elicited tryptase induces endothelial permeability and shock.
The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model.
Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure.
Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.
Enhanced gastrointestinal passive paracellular permeability contributes to the obesity-associated hyperoxaluria.
Rapid differentiation of the human RPE cell line, ARPE-19, induced by nicotinamide.
Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
Japanese encephalitis virus neuropenetrance is driven by mast cell chymase.
Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis.
Canalicular domain structure and function in matrix-free hepatic spheroids.
Generation of an integration-free induced pluripotent stem cell line (FDEENTi003-A) from a patient with pathological myopia.
Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy.
GPR55-mediated effects on brain microvascular endothelial cells and the blood-brain barrier.
p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate.
Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members.
Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-α and Related Pathways.
Bacteroides fragilis Protects Against Antibiotic-Associated Diarrhea in Rats by Modulating Intestinal Defenses.
A convenient protocol for establishing a human cell culture model of the outer retina.
Cadherins in the retinal pigment epithelium (RPE) revisited: P-cadherin is the highly dominant cadherin expressed in human and mouse RPE in vivo.
Photoreceptor Outer Segment Isolation from a Single Canine Retina for RPE Phagocytosis Assay.
Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis.
ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner.
A novel transcriptional network for the androgen receptor in human epididymis epithelial cells.
Characterizing well-differentiated culture of primary human nasal epithelial cells for use in wound healing assays.
Orbital Shear Stress Regulates Differentiation and Barrier Function of Primary Renal Tubular Epithelial Cells.
Cardiac specific PRMT1 ablation causes heart failure through CaMKII dysregulation.
Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity.
Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling.
Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis.
Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity.
Mesenchymal Cells Affect Salivary Epithelial Cell Morphology on PGS/PLGA Core/Shell Nanofibers.
A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testing.
Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
Characterization of cell-cell junction changes associated with the formation of a strong endothelial barrier.
Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.
Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions.
Epidermal growth factor receptor function in the human urothelium.
Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty.
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium.
Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NF-κB in epicardial EMT.
Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers.
Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions.
Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma.
Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca(2+)-dependent Cl(-) currents in human RPE.
Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
Storage of Porcine Cornea in an Innovative Bioreactor.
Isolation and Cultivation of Primary Brain Endothelial Cells from Adult Mice.
Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands.
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Development of a zebrafish sepsis model for high-throughput drug discovery.
Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers.
Matrix stiffening promotes a tumor vasculature phenotype.
mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis.
Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium.
Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model.
Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro.
The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry.
Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity.
Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs).
A new strategy to measure intercellular adhesion forces in mature cell-cell contacts.
Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane.
Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum.
Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions.
A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction.
The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity.
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its Permeability.
Hypertonic saline alleviates experimentally induced cerebral oedema through suppression of vascular endothelial growth factor and its receptor VEGFR2 expression in astrocytes.
Quantification of Confocal Images Using LabVIEW for Tissue Engineering Applications.
Δ(9)-Tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB(2) receptors.
An in vitro model of murine middle ear epithelium.
PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position.
Epithelial cell lines of the cotton rat (Sigmodon hispidus) are highly susceptible in vitro models to zoonotic Bunya-, Rhabdo-, and Flaviviruses.
Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon.
Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells.
Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown.
Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.
The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite.
Dynamics of BMP and Hes1/Hairy1 signaling in the dorsal neural tube underlies the transition from neural crest to definitive roof plate.
Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells.
Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration.
Leukocyte Infiltration Triggers Seizure Recurrence in a Rat Model of Temporal Lobe Epilepsy.
GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells.
CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis.
Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization.
Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.
Intestinal barrier analysis by assessment of mucins, tight junctions, and α-defensins in healthy C57BL/6J and BALB/cJ mice.
3D map of the human corneal endothelial cell.
Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling.
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction.
Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration.
High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells.
Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.
Cutting and Decellularization of Multiple Corneal Stromal Lamellae for the Bioengineering of Endothelial Grafts.
Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption.
In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart.
Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures - a new donor for cell therapy.
NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration.
Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons.
Annexin A3 Regulates Early Blood Vessel Formation.
Junctional abnormalities in human airway epithelial cells expressing F508del CFTR.
Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice.
Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing.
17β-estradiol inhibits MMP-9 and SUR1/TrpM4 expression and activation and thereby attenuates BSCB disruption/hemorrhage after spinal cord injury in male rats.
Effect of differentiation on endocytic profiles of endothelial and epithelial cell culture models.
Regulation of age-related macular degeneration-like pathology by complement factor H.
Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells.
The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.
The Polarity Protein Pals1 Regulates Radial Sorting of Axons.
FGF8 coordinates tissue elongation and cell epithelialization during early kidney tubulogenesis.
Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers.
The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye.
ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer.
Human Alpha-Defensin HNP1 Increases HIV Traversal of the Epithelial Barrier: A Potential Role in STI-Mediated Enhancement of HIV Transmission.
Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E.
Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa.
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells.
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration.
In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.
Bat airway epithelial cells: a novel tool for the study of zoonotic viruses.
Delayed near-infrared analysis permits visualization of rodent retinal pigment epithelium layer in vivo.
Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects.
MAGI-2 is critical for the formation and maintenance of the glomerular filtration barrier in mouse kidney.
MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells.
Polymeric nanocarriers for transport modulation across the pulmonary epithelium: dendrimers, polymeric nanoparticles, and their nanoblends.
Mast cells protect against Pseudomonas aeruginosa-induced lung injury.
Effect of retinoic acid on the tight junctions of the retinal pigment epithelium-choroid complex of guinea pigs with lens-induced myopia in vivo.
Notch signaling maintains neural rosette polarity.
Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.
Histopathological, immunohistochemical criteria and confocal laser-scanning data of arthrofibrosis.
A2E accumulation influences retinal microglial activation and complement regulation.
Apical sorting of lysoGPI-anchored proteins occurs independent of association with detergent-resistant membranes but dependent on their N-glycosylation.
Corneal endothelial cell fate is maintained by LGR5 through the regulation of hedgehog and Wnt pathway.
Small molecule mediated proliferation of primary retinal pigment epithelial cells.
Lumican expression, localization and antitumor activity in prostate cancer.
Unique cell type-specific junctional complexes in vascular endothelium of human and rat liver sinusoids.
Defects in the outer limiting membrane are associated with rosette development in the Nrl-/- retina.
CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells.
Distinct distribution of the tensin family in the mouse kidney and small intestine.
Identification of new binding partners of the chemosensory signaling protein Gγ13 expressed in taste and olfactory sensory cells.
Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research.
Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis.
Redistribution of adhering junctions in human endometrial epithelial cells during the implantation window of the menstrual cycle.
HIF-1 is involved in high glucose-induced paracellular permeability of brain endothelial cells.
Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa.
Extracellular matrix assembly and 3D organization during paraxial mesoderm development in the chick embryo.
Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts.
Dynamics of claudins expression in colitis and colitis-associated cancer in rat.
The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro.
Cell culture models using rat primary alveolar type I cells.
Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endoderm.
LGN-dependent orientation of cell divisions in the dermomyotome controls lineage segregation into muscle and dermis.
MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development.
N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct.
Secondary neurulation: Fate-mapping and gene manipulation of the neural tube in tail bud.
The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.
Correlating cell behavior with tissue topology in embryonic epithelia.
Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development.
A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells.
Microscopic mammalian retinal pigment epithelium lesions induce widespread proliferation with differences in magnitude between center and periphery.
Acute and chronic deficits in the urinary bladder after spinal contusion injury in the adult rat.
Ultrastructure and regulation of lateralized connexin43 in the failing heart.
Molecular staging of epithelial maturation using secretory cell-specific genes as markers.
RhoA and microtubule dynamics control cell-basement membrane interaction in EMT during gastrulation.
Functionally specialized junctions between endothelial cells of lymphatic vessels.
Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium.
ZO-1 is required for protein kinase C gamma-driven disassembly of connexin 43.
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
Zhang L, Tang S, Ma Y, Liu J, Monnier P, Li H, Zhang R, Yu G, Zhang M, Li Y, Feng J, Qin X
Frontiers in immunology 2022;13:861486
Frontiers in immunology 2022;13:861486
Effect of heated tobacco products and traditional cigarettes on pulmonary toxicity and SARS-CoV-2-induced lung injury.
Tsou HH, Wang PH, Ting TH, Ping YH, Liu TY, Cheng HW, Wang HT
Toxicology 2022 Sep;479:153318
Toxicology 2022 Sep;479:153318
Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium.
Hazim RA, Paniagua AE, Tang L, Yang K, Kim KKO, Stiles L, Divakaruni AS, Williams DS
The Journal of biological chemistry 2022 Sep;298(9):102286
The Journal of biological chemistry 2022 Sep;298(9):102286
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome.
Sifat AE, Archie SR, Nozohouri S, Villalba H, Zhang Y, Sharma S, Ghanwatkar Y, Vaidya B, Mara D, Cucullo L, Abbruscato TJ
Fluids and barriers of the CNS 2022 Sep 9;19(1):74
Fluids and barriers of the CNS 2022 Sep 9;19(1):74
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier.
Ayloo S, Lazo CG, Sun S, Zhang W, Cui B, Gu C
Neuron 2022 May 18;110(10):1641-1655.e6
Neuron 2022 May 18;110(10):1641-1655.e6
Circular RNA circ-FoxO3 attenuates blood-brain barrier damage by inducing autophagy during ischemia/reperfusion.
Yang Z, Huang C, Wen X, Liu W, Huang X, Li Y, Zang J, Weng Z, Lu D, Tsang CK, Li K, Xu A
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1275-1287
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1275-1287
Cell-Fibronectin Interactions and Actomyosin Contractility Regulate the Segmentation Clock and Spatio-Temporal Somite Cleft Formation during Chick Embryo Somitogenesis.
Gomes de Almeida P, Rifes P, Martins-Jesus AP, Pinheiro GG, Andrade RP, Thorsteinsdóttir S
Cells 2022 Jun 22;11(13)
Cells 2022 Jun 22;11(13)
DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction.
Chou HC, Cheng CM, Yang CH, Lin TY, Liu YW, Tan TH, Chen YR
Journal of biomedical science 2022 Jun 15;29(1):40
Journal of biomedical science 2022 Jun 15;29(1):40
Effects of intermittent hypoxia with thrombin in an in vitro model of human brain endothelial cells and their impact on PAR-1/PAR-3 cleavage.
Zolotoff C, Puech C, Roche F, Perek N
Scientific reports 2022 Jul 19;12(1):12305
Scientific reports 2022 Jul 19;12(1):12305
A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups.
Landowski M, Bhute VJ, Takimoto T, Grindel S, Shahi PK, Pattnaik BR, Ikeda S, Ikeda A
Scientific reports 2022 Jan 14;12(1):756
Scientific reports 2022 Jan 14;12(1):756
Murine Beta-Amyloid (1-42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors.
Yue Q, Zhou X, Zhang Z, Hoi MPM
International journal of molecular sciences 2022 Feb 7;23(3)
International journal of molecular sciences 2022 Feb 7;23(3)
The interplay between SARS-CoV-2 infected airway epithelium and immune cells modulates regulatory/inflammatory signals.
Bordoni V, Matusali G, Mariotti D, Antonioli M, Cimini E, Sacchi A, Tartaglia E, Casetti R, Grassi G, Notari S, Castilletti C, Fimia GM, Capobianchi MR, Ippolito G, Agrati C
iScience 2022 Feb 18;25(2):103854
iScience 2022 Feb 18;25(2):103854
Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells.
Zhu Y, Chew KY, Wu M, Karawita AC, McCallum G, Steele LE, Yamamoto A, Labzin LI, Yarlagadda T, Khromykh AA, Wang X, Sng JDJ, Stocks CJ, Xia Y, Kollmann TR, Martino D, Joensuu M, Meunier FA, Balistreri G, Bielefeldt-Ohmann H, Bowen AC, Kicic A, Sly PD, Spann KM, Short KR
PLoS biology 2022 Aug;20(8):e3001728
PLoS biology 2022 Aug;20(8):e3001728
Food-Derived High Arginine Peptides Promote Spermatogenesis Recovery in Busulfan Treated Mice.
Liu W, Zhang L, Gao A, Khawar MB, Gao F, Li W
Frontiers in cell and developmental biology 2021;9:791471
Frontiers in cell and developmental biology 2021;9:791471
Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.
Xia Y, Li Y, Khalid W, Bikson M, Fu BM
Frontiers in cell and developmental biology 2021;9:731028
Frontiers in cell and developmental biology 2021;9:731028
The Impact of Particulate Matter (PM2.5) on Human Retinal Development in hESC-Derived Retinal Organoids.
Zeng Y, Li M, Zou T, Chen X, Li Q, Li Y, Ge L, Chen S, Xu H
Frontiers in cell and developmental biology 2021;9:607341
Frontiers in cell and developmental biology 2021;9:607341
Longitudinal [(18)F]FDG and [(13)N]NH(3) PET/CT imaging of brain and spinal cord in a canine hemisection spinal cord injury model.
Zhang L, López-Picón FR, Jia Y, Chen Y, Li J, Han C, Zhuang X, Xia H
NeuroImage. Clinical 2021;31:102692
NeuroImage. Clinical 2021;31:102692
ID4 Is Required for Normal Ependymal Cell Development.
Rocamonde B, Herranz-Pérez V, Garcia-Verdugo JM, Huillard E
Frontiers in neuroscience 2021;15:668243
Frontiers in neuroscience 2021;15:668243
Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages.
Wang R, Song W, Xie C, Zhong W, Xu H, Zhou Q, Deng Y, Hong Y, Li X, Fang M
Journal of inflammation research 2021;14:1973-1989
Journal of inflammation research 2021;14:1973-1989
Role of miRNA-671-5p in Mediating Wnt/β-Catenin-Triggered Podocyte Injury.
Wang C, Liu J, Zhang X, Chen Q, Bai X, Hong X, Zhou L, Liu Y
Frontiers in pharmacology 2021;12:784489
Frontiers in pharmacology 2021;12:784489
Endothelial Thioredoxin-Interacting Protein Depletion Reduces Hemorrhagic Transformation in Hyperglycemic Mice after Embolic Stroke and Thrombolytic Therapy.
Salman M, Ismael S, Li L, Ahmed HA, Puchowicz MA, Ishrat T
Pharmaceuticals (Basel, Switzerland) 2021 Sep 27;14(10)
Pharmaceuticals (Basel, Switzerland) 2021 Sep 27;14(10)
Multi-level inhibition of coronavirus replication by chemical ER stress.
Shaban MS, Müller C, Mayr-Buro C, Weiser H, Meier-Soelch J, Albert BV, Weber A, Linne U, Hain T, Babayev I, Karl N, Hofmann N, Becker S, Herold S, Schmitz ML, Ziebuhr J, Kracht M
Nature communications 2021 Sep 20;12(1):5536
Nature communications 2021 Sep 20;12(1):5536
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Xu SY, Bian HJ, Shu S, Xia SN, Gu Y, Zhang MJ, Xu Y, Cao X
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption.
Pediaditakis I, Kodella KR, Manatakis DV, Le CY, Hinojosa CD, Tien-Street W, Manolakos ES, Vekrellis K, Hamilton GA, Ewart L, Rubin LL, Karalis K
Nature communications 2021 Oct 8;12(1):5907
Nature communications 2021 Oct 8;12(1):5907
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.
Belicova L, Repnik U, Delpierre J, Gralinska E, Seifert S, Valenzuela JI, Morales-Navarrete HA, Franke C, Räägel H, Shcherbinina E, Prikazchikova T, Koteliansky V, Vingron M, Kalaidzidis YL, Zatsepin T, Zerial M
The Journal of cell biology 2021 Oct 4;220(10)
The Journal of cell biology 2021 Oct 4;220(10)
B6 Mouse Strain: The Best Fit for LPS-Induced Interstitial Cystitis Model.
Chen CH, Liao CH, Chen KC, Wang KL, Tseng XW, Tsai WK, Chiang HS, Wu YN
International journal of molecular sciences 2021 Nov 8;22(21)
International journal of molecular sciences 2021 Nov 8;22(21)
Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids.
Buck VU, Kohlen MT, Sternberg AK, Rösing B, Neulen J, Leube RE, Classen-Linke I
Histochemistry and cell biology 2021 May;155(5):581-591
Histochemistry and cell biology 2021 May;155(5):581-591
miR-200c-3p Regulates Epitelial-to-Mesenchymal Transition in Epicardial Mesothelial Cells by Targeting Epicardial Follistatin-Related Protein 1.
Pontemezzo E, Foglio E, Vernucci E, Magenta A, D'Agostino M, Sileno S, Astanina E, Bussolino F, Pellegrini L, Germani A, Russo MA, Limana F
International journal of molecular sciences 2021 May 7;22(9)
International journal of molecular sciences 2021 May 7;22(9)
Functional model of rat thyroid follicles cultured in Matrigel.
Khoruzhenko A, Miot F, Massart C, Van Sande J, Dumont JE, Beauwens R, Boom A
Endocrine connections 2021 May 24;10(5):570-578
Endocrine connections 2021 May 24;10(5):570-578
The anesthetic sevoflurane induces tau trafficking from neurons to microglia.
Dong Y, Liang F, Huang L, Fang F, Yang G, Tanzi RE, Zhang Y, Quan Q, Xie Z
Communications biology 2021 May 12;4(1):560
Communications biology 2021 May 12;4(1):560
Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells.
Janssen AWF, Duivenvoorde LPM, Rijkers D, Nijssen R, Peijnenburg AACM, van der Zande M, Louisse J
Archives of toxicology 2021 Mar;95(3):907-922
Archives of toxicology 2021 Mar;95(3):907-922
Apico-basal cell compression regulates Lamin A/C levels in epithelial tissues.
Iyer KV, Taubenberger A, Zeidan SA, Dye NA, Eaton S, Jülicher F
Nature communications 2021 Mar 25;12(1):1756
Nature communications 2021 Mar 25;12(1):1756
Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS, Lebkowski J, Johnson LV, Clegg DO
Scientific reports 2021 Mar 18;11(1):6286
Scientific reports 2021 Mar 18;11(1):6286
A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications.
Munis AM, Hyde SC, Gill DR
Molecular therapy. Methods & clinical development 2021 Mar 12;20:237-246
Molecular therapy. Methods & clinical development 2021 Mar 12;20:237-246
A Novel Vasoactive Peptide "PG1" from Buffalo Ice-Cream Protects from Angiotensin-Evoked High Blood Pressure.
Carrizzo A, Basilicata MG, Pepe G, Sørensen KK, Ciccarelli M, Sarno VD, Damato A, Venturini E, Borrelli A, Musella S, Abate M, Pietro PD, Ostacolo C, Campiglia P, Vecchione C
Antioxidants (Basel, Switzerland) 2021 Mar 12;10(3)
Antioxidants (Basel, Switzerland) 2021 Mar 12;10(3)
APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer's mice via cyclophilin A independently of amyloid-β.
Montagne A, Nikolakopoulou AM, Huuskonen MT, Sagare AP, Lawson EJ, Lazic D, Rege SV, Grond A, Zuniga E, Barnes SR, Prince J, Sagare M, Hsu CJ, LaDu MJ, Jacobs RE, Zlokovic BV
Nature aging 2021 Jun;1(6):506-520
Nature aging 2021 Jun;1(6):506-520
Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers.
Kadry H, Noorani B, Bickel U, Abbruscato TJ, Cucullo L
Fluids and barriers of the CNS 2021 Jun 22;18(1):28
Fluids and barriers of the CNS 2021 Jun 22;18(1):28
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration.
Pérez-González C, Ceada G, Greco F, Matejčić M, Gómez-González M, Castro N, Menendez A, Kale S, Krndija D, Clark AG, Gannavarapu VR, Álvarez-Varela A, Roca-Cusachs P, Batlle E, Vignjevic DM, Arroyo M, Trepat X
Nature cell biology 2021 Jul;23(7):745-757
Nature cell biology 2021 Jul;23(7):745-757
Molecular Mechanism of Stimulation of Na-K-ATPase by Leukotriene D4 in Intestinal Epithelial Cells.
Nepal N, Arthur S, Butts MR, Singh S, Palaniappan B, Sundaram U
International journal of molecular sciences 2021 Jul 15;22(14)
International journal of molecular sciences 2021 Jul 15;22(14)
Epithelial Regeneration in Human Corneas Preserved in an Active Storage Machine.
Guindolet D, Crouzet E, He Z, Herbepin P, Perrache C, Garcin T, Gauthier AS, Forest F, Peoc'h M, Gain P, Gabison E, Thuret G
Translational vision science & technology 2021 Feb 5;10(2):31
Translational vision science & technology 2021 Feb 5;10(2):31
In vitro Measurement of Membrane Attack Complex in RPE Cells.
Mulfaul K, Doyle SL
Bio-protocol 2021 Feb 20;11(4):e3916
Bio-protocol 2021 Feb 20;11(4):e3916
Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries.
Olivera GC, Ross EC, Peuckert C, Barragan A
eLife 2021 Dec 8;10
eLife 2021 Dec 8;10
Lactobacillus casei and Epidermal Growth Factor Prevent Osmotic Stress-Induced Tight Junction Disruption in Caco-2 Cell Monolayers.
Samak G, Rao R, Rao R
Cells 2021 Dec 18;10(12)
Cells 2021 Dec 18;10(12)
Low-Intensity Extracorporeal Shock Wave Therapy Promotes Bladder Regeneration and Improves Overactive Bladder Induced by Ovarian Hormone Deficiency from Rat Animal Model to Human Clinical Trial.
Lin KL, Lu JH, Chueh KS, Juan TJ, Wu BN, Chuang SM, Lee YC, Shen MC, Long CY, Juan YS
International journal of molecular sciences 2021 Aug 27;22(17)
International journal of molecular sciences 2021 Aug 27;22(17)
Diammonium glycyrrhizinate lipid ligand ameliorates lipopolysaccharide-induced acute lung injury by modulating vascular endothelial barrier function.
Liu MM, Zhou J, Ji D, Yang J, Huang YP, Wang Q
Experimental and therapeutic medicine 2021 Apr;21(4):303
Experimental and therapeutic medicine 2021 Apr;21(4):303
Real-Time Monitoring the Effect of Cytopathic Hypoxia on Retinal Pigment Epithelial Barrier Functionality Using Electric Cell-Substrate Impedance Sensing (ECIS) Biosensor Technology.
Guerra MH, Yumnamcha T, Ebrahim AS, Berger EA, Singh LP, Ibrahim AS
International journal of molecular sciences 2021 Apr 27;22(9)
International journal of molecular sciences 2021 Apr 27;22(9)
Imaging the Cell Morphological Response to 3D Topography and Curvature in Engineered Intestinal Tissues.
Altay G, Tosi S, García-Díaz M, Martínez E
Frontiers in bioengineering and biotechnology 2020;8:294
Frontiers in bioengineering and biotechnology 2020;8:294
Site-specific opening of the blood-brain barrier by extracellular histones.
Villalba N, Baby S, Cha BJ, Yuan SY
Journal of neuroinflammation 2020 Sep 22;17(1):281
Journal of neuroinflammation 2020 Sep 22;17(1):281
Protocol for Differentiation of Human iPSCs into Pulmonary Neuroendocrine Cells.
Hor P, Ichida JK, Borok Z, Ryan AL
STAR protocols 2020 Sep 18;1(2):100068
STAR protocols 2020 Sep 18;1(2):100068
Modulation of Tmem135 Leads to Retinal Pigmented Epithelium Pathologies in Mice.
Landowski M, Grindel S, Shahi PK, Johnson A, Western D, Race A, Shi F, Benson J, Gao M, Santoirre E, Lee WH, Ikeda S, Pattnaik BR, Ikeda A
Investigative ophthalmology & visual science 2020 Oct 1;61(12):16
Investigative ophthalmology & visual science 2020 Oct 1;61(12):16
Treatment with interleukin-33 is non-toxic and protects retinal pigment epithelium in an ageing model of outer retinal degeneration.
Clare AJ, Copland DA, Nicholson LB, Liu J, Neal CR, Moss S, Dick AD, Theodoropoulou S
Journal of cellular and molecular medicine 2020 Nov;24(22):13546-13550
Journal of cellular and molecular medicine 2020 Nov;24(22):13546-13550
High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function.
Grosheva I, Zheng D, Levy M, Polansky O, Lichtenstein A, Golani O, Dori-Bachash M, Moresi C, Shapiro H, Del Mare-Roumani S, Valdes-Mas R, He Y, Karbi H, Chen M, Harmelin A, Straussman R, Yissachar N, Elinav E, Geiger B
Gastroenterology 2020 Nov;159(5):1807-1823
Gastroenterology 2020 Nov;159(5):1807-1823
Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD.
Osan JK, Talukdar SN, Feldmann F, DeMontigny BA, Jerome K, Bailey KL, Feldmann H, Mehedi M
bioRxiv : the preprint server for biology 2020 Nov 12;
bioRxiv : the preprint server for biology 2020 Nov 12;
D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration.
Wang B, Wang L, Gu S, Yu Y, Huang H, Mo K, Xu H, Zeng F, Xiao Y, Peng L, Liu C, Cao N, Liu Y, Yuan J, Ouyang H
Signal transduction and targeted therapy 2020 Mar 4;5(1):20
Signal transduction and targeted therapy 2020 Mar 4;5(1):20
Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells.
Plaza Reyes A, Petrus-Reurer S, Padrell Sánchez S, Kumar P, Douagi I, Bartuma H, Aronsson M, Westman S, Lardner E, André H, Falk A, Nandrot EF, Kvanta A, Lanner F
Nature communications 2020 Mar 30;11(1):1609
Nature communications 2020 Mar 30;11(1):1609
Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance.
Roudnicky F, Kim BK, Lan Y, Schmucki R, Küppers V, Christensen K, Graf M, Patsch C, Burcin M, Meyer CA, Westenskow PD, Cowan CA
Scientific reports 2020 Mar 3;10(1):3886
Scientific reports 2020 Mar 3;10(1):3886
EGF and a GSK3 Inhibitor Deplete Junctional E-cadherin and Stimulate Proliferation in the Mature Mammalian Ear.
Kozlowski MM, Rudolf MA, Corwin JT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Mar 25;40(13):2618-2632
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Mar 25;40(13):2618-2632
Protective effect of emodin on intestinal epithelial tight junction barrier integrity in rats with sepsis induced by cecal ligation and puncture.
Li Y, Guo R, Zhang M, Chen P, Li J, Sun Y
Experimental and therapeutic medicine 2020 Jun;19(6):3521-3530
Experimental and therapeutic medicine 2020 Jun;19(6):3521-3530
TIMP1 preserves the blood-brain barrier through interacting with CD63/integrin β 1 complex and regulating downstream FAK/RhoA signaling.
Tang J, Kang Y, Huang L, Wu L, Peng Y
Acta pharmaceutica Sinica. B 2020 Jun;10(6):987-1003
Acta pharmaceutica Sinica. B 2020 Jun;10(6):987-1003
Hedgehog Signaling Regulates Epithelial Morphogenesis to Position the Ventral Embryonic Midline.
Arraf AA, Yelin R, Reshef I, Jadon J, Abboud M, Zaher M, Schneider J, Vladimirov FK, Schultheiss TM
Developmental cell 2020 Jun 8;53(5):589-602.e6
Developmental cell 2020 Jun 8;53(5):589-602.e6
Astrocyte-derived VEGF increases cerebral microvascular permeability under high salt conditions.
Deng Z, Zhou L, Wang Y, Liao S, Huang Y, Shan Y, Tan S, Zeng Q, Peng L, Huang H, Lu Z
Aging 2020 Jun 22;12(12):11781-11793
Aging 2020 Jun 22;12(12):11781-11793
Anisakis simplex products impair intestinal epithelial barrier function and occludin and zonula occludens-1 localisation in differentiated Caco-2 cells.
Carballeda-Sangiao N, Sánchez-Alonso I, Navas A, Arcos SC, de Palencia PF, Careche M, González-Muñoz M
PLoS neglected tropical diseases 2020 Jul;14(7):e0008462
PLoS neglected tropical diseases 2020 Jul;14(7):e0008462
Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform.
Kutys ML, Polacheck WJ, Welch MK, Gagnon KA, Koorman T, Kim S, Li L, McClatchey AI, Chen CS
Nature communications 2020 Jul 6;11(1):3377
Nature communications 2020 Jul 6;11(1):3377
Targeting QKI-7 in vivo restores endothelial cell function in diabetes.
Yang C, Eleftheriadou M, Kelaini S, Morrison T, González MV, Caines R, Edwards N, Yacoub A, Edgar K, Moez A, Ivetic A, Zampetaki A, Zeng L, Wilkinson FL, Lois N, Stitt AW, Grieve DJ, Margariti A
Nature communications 2020 Jul 30;11(1):3812
Nature communications 2020 Jul 30;11(1):3812
S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling.
Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS
JCI insight 2020 Jul 23;5(14)
JCI insight 2020 Jul 23;5(14)
Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis.
Liu XX, Yang L, Shao LX, He Y, Wu G, Bao YH, Lu NN, Gong DM, Lu YP, Cui TT, Sun NH, Chen DY, Shi WX, Fukunaga K, Chen HS, Chen Z, Han F, Lu YM
The Journal of experimental medicine 2020 Jan 6;217(1)
The Journal of experimental medicine 2020 Jan 6;217(1)
Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation.
Hamidi S, Nakaya Y, Nagai H, Alev C, Kasukawa T, Chhabra S, Lee R, Niwa H, Warmflash A, Shibata T, Sheng G
Development (Cambridge, England) 2020 Feb 3;147(3)
Development (Cambridge, England) 2020 Feb 3;147(3)
Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration.
Mulfaul K, Ozaki E, Fernando N, Brennan K, Chirco KR, Connolly E, Greene C, Maminishkis A, Salomon RG, Linetsky M, Natoli R, Mullins RF, Campbell M, Doyle SL
Cell reports 2020 Feb 18;30(7):2209-2224.e5
Cell reports 2020 Feb 18;30(7):2209-2224.e5
Actin-Binding Protein Cortactin Promotes Pathogenesis of Experimental Autoimmune Encephalomyelitis by Supporting Leukocyte Infiltration into the Central Nervous System.
Samus M, Li YT, Sorokin L, Rottner K, Vestweber D
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Feb 12;40(7):1389-1404
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020 Feb 12;40(7):1389-1404
Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.
Sun WR, Ramirez S, Spiller KE, Zhao Y, Fuhrmann S
Human molecular genetics 2020 Dec 18;29(20):3373-3387
Human molecular genetics 2020 Dec 18;29(20):3373-3387
YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.
Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS
Development (Cambridge, England) 2020 Dec 13;147(23)
Development (Cambridge, England) 2020 Dec 13;147(23)
Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung's disease.
Dariel A, Grynberg L, Auger M, Lefèvre C, Durand T, Aubert P, Le Berre-Scoul C, Venara A, Suply E, Leclair MD, de Vries P, Levard G, Parmentier B, Podevin G, Schmitt F, Couvrat V, Irtan S, Hervieux E, Villemagne T, Lardy H, Capito C, Muller C, Sarnacki S, Mosnier JF, Galmiche L, Derkinderen P, Boudin H, Brochard C, Neunlist M
Scientific reports 2020 Dec 10;10(1):21725
Scientific reports 2020 Dec 10;10(1):21725
Syncytia formation by SARS-CoV-2-infected cells.
Buchrieser J, Dufloo J, Hubert M, Monel B, Planas D, Rajah MM, Planchais C, Porrot F, Guivel-Benhassine F, Van der Werf S, Casartelli N, Mouquet H, Bruel T, Schwartz O
The EMBO journal 2020 Dec 1;39(23):e106267
The EMBO journal 2020 Dec 1;39(23):e106267
An organoid model to assay the role of CFTR in the human epididymis epithelium.
Leir SH, Yin S, Kerschner JL, Xia S, Ahmadi S, Bear C, Harris A
Cell and tissue research 2020 Aug;381(2):327-336
Cell and tissue research 2020 Aug;381(2):327-336
Soy Protein Nanofiber Scaffolds for Uniform Maturation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.
Phelan MA, Kruczek K, Wilson JH, Brooks MJ, Drinnan CT, Regent F, Gerstenhaber JA, Swaroop A, Lelkes PI, Li T
Tissue engineering. Part C, Methods 2020 Aug;26(8):433-446
Tissue engineering. Part C, Methods 2020 Aug;26(8):433-446
Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms.
Wandel MP, Kim BH, Park ES, Boyle KB, Nayak K, Lagrange B, Herod A, Henry T, Zilbauer M, Rohde J, MacMicking JD, Randow F
Nature immunology 2020 Aug;21(8):880-891
Nature immunology 2020 Aug;21(8):880-891
Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells.
Zhu N, Wang W, Liu Z, Liang C, Wang W, Ye F, Huang B, Zhao L, Wang H, Zhou W, Deng Y, Mao L, Su C, Qiang G, Jiang T, Zhao J, Wu G, Song J, Tan W
Nature communications 2020 Aug 6;11(1):3910
Nature communications 2020 Aug 6;11(1):3910
Human Fallopian Tube Epithelial Cell Culture Model To Study Host Responses to Chlamydia trachomatis Infection.
McQueen BE, Kiatthanapaiboon A, Fulcher ML, Lam M, Patton K, Powell E, Kollipara A, Madden V, Suchland RJ, Wyrick P, O'Connell CM, Reidel B, Kesimer M, Randell SH, Darville T, Nagarajan UM
Infection and immunity 2020 Aug 19;88(9)
Infection and immunity 2020 Aug 19;88(9)
Interaction of Staphylococcus aureus and Host Cells upon Infection of Bronchial Epithelium during Different Stages of Regeneration.
Palma Medina LM, Becker AK, Michalik S, Surmann K, Hildebrandt P, Gesell Salazar M, Mekonnen SA, Kaderali L, Völker U, van Dijl JM
ACS infectious diseases 2020 Aug 14;6(8):2279-2290
ACS infectious diseases 2020 Aug 14;6(8):2279-2290
The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study.
Sivandzade F, Alqahtani F, Sifat A, Cucullo L
Journal of neuroinflammation 2020 Apr 27;17(1):133
Journal of neuroinflammation 2020 Apr 27;17(1):133
HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells.
Liao K, Niu F, Hu G, Guo ML, Sil S, Buch S
Tissue barriers 2020 Apr 2;8(2):1748983
Tissue barriers 2020 Apr 2;8(2):1748983
The Circadian Clock Gene Bmal1 Controls Intestinal Exporter MRP2 and Drug Disposition.
Yu F, Zhang T, Zhou C, Xu H, Guo L, Chen M, Wu B
Theranostics 2019;9(10):2754-2767
Theranostics 2019;9(10):2754-2767
Metformin Improves Fertility in Obese Males by Alleviating Oxidative Stress-Induced Blood-Testis Barrier Damage.
Ye J, Luo D, Xu X, Sun M, Su X, Tian Z, Zhang M, Yu C, Guan Q
Oxidative medicine and cellular longevity 2019;2019:9151067
Oxidative medicine and cellular longevity 2019;2019:9151067
Lactobacillus fermentum species ameliorate dextran sulfate sodium-induced colitis by regulating the immune response and altering gut microbiota.
Jang YJ, Kim WK, Han DH, Lee K, Ko G
Gut microbes 2019;10(6):696-711
Gut microbes 2019;10(6):696-711
Poly-ε-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation.
Kennedy S, Lace R, Carserides C, Gallagher AG, Wellings DA, Williams RL, Levis HJ
Journal of materials science. Materials in medicine 2019 Sep 4;30(9):102
Journal of materials science. Materials in medicine 2019 Sep 4;30(9):102
Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.
Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, Shibuya A, Fasano A, Kiyono H, Abe M, Tatsumoto N, Yamashita M, Crother TR, Shimada K, Arditi M
Immunity 2019 Sep 17;51(3):508-521.e6
Immunity 2019 Sep 17;51(3):508-521.e6
Hepatic progenitor cell activation is induced by the depletion of the gut microbiome in mice.
Wang F, Sun NN, Li LL, Zhu WW, Xiu J, Shen Y, Xu Q
MicrobiologyOpen 2019 Oct;8(10):e873
MicrobiologyOpen 2019 Oct;8(10):e873
Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.
Nakamura K, Ikeuchi T, Nara K, Rhodes CS, Zhang P, Chiba Y, Kazuno S, Miura Y, Ago T, Arikawa-Hirasawa E, Mukouyama YS, Yamada Y
The Journal of cell biology 2019 Oct 7;218(10):3506-3525
The Journal of cell biology 2019 Oct 7;218(10):3506-3525
BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration.
Liu M, Sun T, Li N, Peng J, Fu D, Li W, Li L, Gao WQ
Nature communications 2019 Oct 10;10(1):4614
Nature communications 2019 Oct 10;10(1):4614
Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies.
Kang HM, Lim JH, Noh KH, Park D, Cho HS, Susztak K, Jung CR
Scientific reports 2019 Nov 26;9(1):17610
Scientific reports 2019 Nov 26;9(1):17610
Fusarium Mycotoxins Disrupt the Barrier and Induce IL-6 Release in a Human Placental Epithelium Cell Line.
Seyed Toutounchi N, Hogenkamp A, Varasteh S, Van't Land B, Garssen J, Kraneveld AD, Folkerts G, Braber S
Toxins 2019 Nov 14;11(11)
Toxins 2019 Nov 14;11(11)
Nanoparticle induced barrier function assessment at liquid-liquid and air-liquid interface in novel human lung epithelia cell lines.
Leibrock L, Wagener S, Singh AV, Laux P, Luch A
Toxicology research 2019 Nov 1;8(6):1016-1027
Toxicology research 2019 Nov 1;8(6):1016-1027
Foxc2 is essential for podocyte function.
Nilsson D, Heglind M, Arani Z, Enerbäck S
Physiological reports 2019 May;7(9):e14083
Physiological reports 2019 May;7(9):e14083
Organoid-derived C-Kit(+)/SSEA4(-) human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents.
Zou T, Gao L, Zeng Y, Li Q, Li Y, Chen S, Hu X, Chen X, Fu C, Xu H, Yin ZQ
Nature communications 2019 Mar 14;10(1):1205
Nature communications 2019 Mar 14;10(1):1205
Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
Storti F, Klee K, Todorova V, Steiner R, Othman A, van der Velde-Visser S, Samardzija M, Meneau I, Barben M, Karademir D, Pauzuolyte V, Boye SL, Blaser F, Ullmer C, Dunaief JL, Hornemann T, Rohrer L, den Hollander A, von Eckardstein A, Fingerle J, Maugeais C, Grimm C
eLife 2019 Mar 13;8
eLife 2019 Mar 13;8
Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
Artegiani B, van Voorthuijsen L, Lindeboom RGH, Seinstra D, Heo I, Tapia P, López-Iglesias C, Postrach D, Dayton T, Oka R, Hu H, van Boxtel R, van Es JH, Offerhaus J, Peters PJ, van Rheenen J, Vermeulen M, Clevers H
Cell stem cell 2019 Jun 6;24(6):927-943.e6
Cell stem cell 2019 Jun 6;24(6):927-943.e6
DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins.
Ye ZY, Xing HY, Wang B, Liu M, Lv PY
Chinese medical journal 2019 Jun 5;132(11):1344-1353
Chinese medical journal 2019 Jun 5;132(11):1344-1353
Dengue virus-elicited tryptase induces endothelial permeability and shock.
Rathore AP, Mantri CK, Aman SA, Syenina A, Ooi J, Jagaraj CJ, Goh CC, Tissera H, Wilder-Smith A, Ng LG, Gubler DJ, St John AL
The Journal of clinical investigation 2019 Jul 2;129(10):4180-4193
The Journal of clinical investigation 2019 Jul 2;129(10):4180-4193
The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model.
Katt ME, Mayo LN, Ellis SE, Mahairaki V, Rothstein JD, Cheng L, Searson PC
Fluids and barriers of the CNS 2019 Jul 15;16(1):20
Fluids and barriers of the CNS 2019 Jul 15;16(1):20
Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure.
Butler MB, Short NE, Maniou E, Alexandre P, Greene NDE, Copp AJ, Galea GL
Journal of cell science 2019 Jul 1;132(13)
Journal of cell science 2019 Jul 1;132(13)
Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.
Kaushik G, Gil DA, Torr E, Berge ES, Soref C, Uhl P, Fontana G, Antosiewicz-Bourget J, Edington C, Schwartz MP, Griffith LG, Thomson JA, Skala MC, Daly WT, Murphy WL
Advanced healthcare materials 2019 Jan;8(2):e1801186
Advanced healthcare materials 2019 Jan;8(2):e1801186
Enhanced gastrointestinal passive paracellular permeability contributes to the obesity-associated hyperoxaluria.
Bashir M, Meddings J, Alshaikh A, Jung D, Le K, Amin R, Ratakonda S, Sharma S, Granja I, Satti M, Asplin J, Hassan H
American journal of physiology. Gastrointestinal and liver physiology 2019 Jan 1;316(1):G1-G14
American journal of physiology. Gastrointestinal and liver physiology 2019 Jan 1;316(1):G1-G14
Rapid differentiation of the human RPE cell line, ARPE-19, induced by nicotinamide.
Hazim RA, Volland S, Yen A, Burgess BL, Williams DS
Experimental eye research 2019 Feb;179:18-24
Experimental eye research 2019 Feb;179:18-24
Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
Landowski M, Kelly U, Klingeborn M, Groelle M, Ding JD, Grigsby D, Bowes Rickman C
Proceedings of the National Academy of Sciences of the United States of America 2019 Feb 26;116(9):3703-3711
Proceedings of the National Academy of Sciences of the United States of America 2019 Feb 26;116(9):3703-3711
Japanese encephalitis virus neuropenetrance is driven by mast cell chymase.
Hsieh JT, Rathore APS, Soundarajan G, St John AL
Nature communications 2019 Feb 11;10(1):706
Nature communications 2019 Feb 11;10(1):706
Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis.
Wang J, Cui Y, Yu Z, Wang W, Cheng X, Ji W, Guo S, Zhou Q, Wu N, Chen Y, Chen Y, Song X, Jiang H, Wang Y, Lan Y, Zhou B, Mao L, Li J, Yang H, Guo W, Yang X
Cell stem cell 2019 Dec 5;25(6):754-767.e9
Cell stem cell 2019 Dec 5;25(6):754-767.e9
Canalicular domain structure and function in matrix-free hepatic spheroids.
Sharma VR, Shrivastava A, Gallet B, Karepina E, Charbonnier P, Chevallet M, Jouneau PH, Deniaud A
Biomaterials science 2019 Dec 17;8(1):485-496
Biomaterials science 2019 Dec 17;8(1):485-496
Generation of an integration-free induced pluripotent stem cell line (FDEENTi003-A) from a patient with pathological myopia.
Bai X, Yang XJ, Chen L
Stem cell research 2019 Aug;39:101495
Stem cell research 2019 Aug;39:101495
Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy.
Hudson N, Celkova L, Hopkins A, Greene C, Storti F, Ozaki E, Fahey E, Theodoropoulou S, Kenna PF, Humphries MM, Curtis AM, Demmons E, Browne A, Liddie S, Lawrence MS, Grimm C, Cahill MT, Humphries P, Doyle SL, Campbell M
JCI insight 2019 Aug 8;4(15)
JCI insight 2019 Aug 8;4(15)
GPR55-mediated effects on brain microvascular endothelial cells and the blood-brain barrier.
Leo LM, Familusi B, Hoang M, Smith R, Lindenau K, Sporici KT, Brailoiu E, Abood ME, Brailoiu GC
Neuroscience 2019 Aug 21;414:88-98
Neuroscience 2019 Aug 21;414:88-98
p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate.
Nyeng P, Heilmann S, Löf-Öhlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H
Developmental cell 2019 Apr 8;49(1):31-47.e9
Developmental cell 2019 Apr 8;49(1):31-47.e9
Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members.
Ortiz-Álvarez G, Daclin M, Shihavuddin A, Lansade P, Fortoul A, Faucourt M, Clavreul S, Lalioti ME, Taraviras S, Hippenmeyer S, Livet J, Meunier A, Genovesio A, Spassky N
Neuron 2019 Apr 3;102(1):159-172.e7
Neuron 2019 Apr 3;102(1):159-172.e7
Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-α and Related Pathways.
Fang M, Zhong WH, Song WL, Deng YY, Yang DM, Xiong B, Zeng HK, Wang HD
Frontiers in pharmacology 2018;9:823
Frontiers in pharmacology 2018;9:823
Bacteroides fragilis Protects Against Antibiotic-Associated Diarrhea in Rats by Modulating Intestinal Defenses.
Zhang W, Zhu B, Xu J, Liu Y, Qiu E, Li Z, Li Z, He Y, Zhou H, Bai Y, Zhi F
Frontiers in immunology 2018;9:1040
Frontiers in immunology 2018;9:1040
A convenient protocol for establishing a human cell culture model of the outer retina.
Lynn SA, Keeling E, Dewing JM, Johnston DA, Page A, Cree AJ, Tumbarello DA, Newman TA, Lotery AJ, Ratnayaka JA
F1000Research 2018;7:1107
F1000Research 2018;7:1107
Cadherins in the retinal pigment epithelium (RPE) revisited: P-cadherin is the highly dominant cadherin expressed in human and mouse RPE in vivo.
Yang X, Chung JY, Rai U, Esumi N
PloS one 2018;13(1):e0191279
PloS one 2018;13(1):e0191279
Photoreceptor Outer Segment Isolation from a Single Canine Retina for RPE Phagocytosis Assay.
Sudharsan R, Elliott MH, Dolgova N, Aguirre GD, Beltran WA
Advances in experimental medicine and biology 2018;1074:593-601
Advances in experimental medicine and biology 2018;1074:593-601
Commensal microbiota induces colonic barrier structure and functions that contribute to homeostasis.
Hayes CL, Dong J, Galipeau HJ, Jury J, McCarville J, Huang X, Wang XY, Naidoo A, Anbazhagan AN, Libertucci J, Sheridan C, Dudeja PK, Bowdish DME, Surette MG, Verdu EF
Scientific reports 2018 Sep 21;8(1):14184
Scientific reports 2018 Sep 21;8(1):14184
ZO-1 protein is required for hydrogen peroxide to increase MDCK cell paracellular permeability in an ERK 1/2-dependent manner.
Bilal S, Jaggi S, Janosevic D, Shah N, Teymour S, Voronina A, Watari J, Axis J, Amsler K
American journal of physiology. Cell physiology 2018 Sep 1;315(3):C422-C431
American journal of physiology. Cell physiology 2018 Sep 1;315(3):C422-C431
A novel transcriptional network for the androgen receptor in human epididymis epithelial cells.
Yang R, Browne JA, Eggener SE, Leir SH, Harris A
Molecular human reproduction 2018 Sep 1;24(9):433-443
Molecular human reproduction 2018 Sep 1;24(9):433-443
Characterizing well-differentiated culture of primary human nasal epithelial cells for use in wound healing assays.
Schagen J, Sly PD, Fantino E
Laboratory investigation; a journal of technical methods and pathology 2018 Nov;98(11):1478-1486
Laboratory investigation; a journal of technical methods and pathology 2018 Nov;98(11):1478-1486
Orbital Shear Stress Regulates Differentiation and Barrier Function of Primary Renal Tubular Epithelial Cells.
Ferrell N, Cheng J, Miao S, Roy S, Fissell WH
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2018 Nov Dec;64(6):766-772
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2018 Nov Dec;64(6):766-772
Cardiac specific PRMT1 ablation causes heart failure through CaMKII dysregulation.
Pyun JH, Kim HJ, Jeong MH, Ahn BY, Vuong TA, Lee DI, Choi S, Koo SH, Cho H, Kang JS
Nature communications 2018 Nov 30;9(1):5107
Nature communications 2018 Nov 30;9(1):5107
Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity.
Lee S, Cieply B, Yang Y, Peart N, Glaser C, Chan P, Carstens RP
Cell reports 2018 Nov 27;25(9):2417-2430.e5
Cell reports 2018 Nov 27;25(9):2417-2430.e5
Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling.
Hübner K, Cabochette P, Diéguez-Hurtado R, Wiesner C, Wakayama Y, Grassme KS, Hubert M, Guenther S, Belting HG, Affolter M, Adams RH, Vanhollebeke B, Herzog W
Nature communications 2018 Nov 19;9(1):4860
Nature communications 2018 Nov 19;9(1):4860
Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
Guo N, Soden ME, Herber C, Kim MT, Besnard A, Lin P, Ma X, Cepko CL, Zweifel LS, Sahay A
Nature medicine 2018 May;24(4):438-449
Nature medicine 2018 May;24(4):438-449
Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis.
Alsaffar H, Martino N, Garrett JP, Adam AP
American journal of physiology. Cell physiology 2018 May 1;314(5):C589-C602
American journal of physiology. Cell physiology 2018 May 1;314(5):C589-C602
Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity.
Jing B, Zhang C, Liu X, Zhou L, Liu J, Yao Y, Yu J, Weng Y, Pan M, Liu J, Wang Z, Sun Y, Sun YE
Protein & cell 2018 Mar;9(3):298-309
Protein & cell 2018 Mar;9(3):298-309
Mesenchymal Cells Affect Salivary Epithelial Cell Morphology on PGS/PLGA Core/Shell Nanofibers.
Sfakis L, Kamaldinov T, Khmaladze A, Hosseini ZF, Nelson DA, Larsen M, Castracane J
International journal of molecular sciences 2018 Mar 29;19(4)
International journal of molecular sciences 2018 Mar 29;19(4)
A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testing.
Miranda-Azpiazu P, Panagiotou S, Jose G, Saha S
Scientific reports 2018 Jun 8;8(1):8784
Scientific reports 2018 Jun 8;8(1):8784
Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
Wilkinson EL, Sidaway JE, Cross MJ
Journal of cellular physiology 2018 Jan;233(1):186-200
Journal of cellular physiology 2018 Jan;233(1):186-200
Characterization of cell-cell junction changes associated with the formation of a strong endothelial barrier.
McRae M, LaFratta LM, Nguyen BM, Paris JJ, Hauser KF, Conway DE
Tissue barriers 2018 Jan 2;6(1):e1405774
Tissue barriers 2018 Jan 2;6(1):e1405774
Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.
Hilfenhaus G, Nguyen DP, Freshman J, Prajapati D, Ma F, Song D, Ziyad S, Cuadrado M, Pellegrini M, Bustelo XR, Iruela-Arispe ML
The Journal of cell biology 2018 Aug 6;217(8):2813-2830
The Journal of cell biology 2018 Aug 6;217(8):2813-2830
Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions.
Liu X, Gu X, Ma W, Oxendine M, Gil HJ, Davis GE, Cleaver O, Oliver G
Development (Cambridge, England) 2018 Aug 20;145(17)
Development (Cambridge, England) 2018 Aug 20;145(17)
Epidermal growth factor receptor function in the human urothelium.
Wasén C, Ekstrand M, Levin M, Giglio D
International urology and nephrology 2018 Apr;50(4):647-656
International urology and nephrology 2018 Apr;50(4):647-656
Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty.
Romano V, Parekh M, Ruzza A, Willoughby CE, Ferrari S, Ponzin D, Kaye SB, Levis HJ
The British journal of ophthalmology 2018 Apr;102(4):549-555
The British journal of ophthalmology 2018 Apr;102(4):549-555
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Gao W, Li F, Zhou Z, Xu X, Wu Y, Zhou S, Yin D, Sun D, Xiong J, Jiang R, Zhang J
Frontiers in neurology 2017;8:281
Frontiers in neurology 2017;8:281
Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium.
Cuellar P, Hernández-Nava E, García-Rivera G, Chávez-Munguía B, Schnoor M, Betanzos A, Orozco E
Frontiers in cellular and infection microbiology 2017;7:372
Frontiers in cellular and infection microbiology 2017;7:372
Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NF-κB in epicardial EMT.
Li Y, Urban A, Midura D, Simon HG, Wang QT
PloS one 2017;12(3):e0174563
PloS one 2017;12(3):e0174563
Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers.
Váradi J, Harazin A, Fenyvesi F, Réti-Nagy K, Gogolák P, Vámosi G, Bácskay I, Fehér P, Ujhelyi Z, Vasvári G, Róka E, Haines D, Deli MA, Vecsernyés M
PloS one 2017;12(1):e0170537
PloS one 2017;12(1):e0170537
Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions.
Bao X, Lian X, Qian T, Bhute VJ, Han T, Palecek SP
Nature protocols 2017 Sep;12(9):1890-1900
Nature protocols 2017 Sep;12(9):1890-1900
Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma.
Higuita-Castro N, Nelson MT, Shukla V, Agudelo-Garcia PA, Zhang W, Duarte-Sanmiguel SM, Englert JA, Lannutti JJ, Hansford DJ, Ghadiali SN
Scientific reports 2017 Sep 14;7(1):11623
Scientific reports 2017 Sep 14;7(1):11623
Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca(2+)-dependent Cl(-) currents in human RPE.
Li Y, Zhang Y, Xu Y, Kittredge A, Ward N, Chen S, Tsang SH, Yang T
eLife 2017 Oct 24;6
eLife 2017 Oct 24;6
Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization.
Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS
Stem cell research & therapy 2017 Oct 2;8(1):217
Stem cell research & therapy 2017 Oct 2;8(1):217
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
Connell M, Chen H, Jiang J, Kuan CW, Fotovati A, Chu TL, He Z, Lengyell TC, Li H, Kroll T, Li AM, Goldowitz D, Frappart L, Ploubidou A, Patel MS, Pilarski LM, Simpson EM, Lange PF, Allan DW, Maxwell CA
eLife 2017 Oct 10;6
eLife 2017 Oct 10;6
Storage of Porcine Cornea in an Innovative Bioreactor.
Guindolet D, Crouzet E, He Z, Herbepin P, Jumelle C, Perrache C, Dumollard JM, Forest F, Peoc'h M, Gain P, Gabison E, Thuret G
Investigative ophthalmology & visual science 2017 Nov 1;58(13):5907-5917
Investigative ophthalmology & visual science 2017 Nov 1;58(13):5907-5917
Isolation and Cultivation of Primary Brain Endothelial Cells from Adult Mice.
Assmann JC, Müller K, Wenzel J, Walther T, Brands J, Thornton P, Allan SM, Schwaninger M
Bio-protocol 2017 May 20;7(10)
Bio-protocol 2017 May 20;7(10)
Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands.
Ding C, Cong X, Zhang XM, Li SL, Wu LL, Yu GY
Journal of molecular histology 2017 Jun;48(3):225-234
Journal of molecular histology 2017 Jun;48(3):225-234
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity.
Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL
Cell research 2017 Jul;27(7):882-897
Cell research 2017 Jul;27(7):882-897
Development of a zebrafish sepsis model for high-throughput drug discovery.
Philip AM, Wang Y, Mauro A, El-Rass S, Marshall JC, Lee WL, Slutsky AS, dosSantos CC, Wen XY
Molecular medicine (Cambridge, Mass.) 2017 Jul;23:134-148
Molecular medicine (Cambridge, Mass.) 2017 Jul;23:134-148
Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers.
Klingeborn M, Dismuke WM, Skiba NP, Kelly U, Stamer WD, Bowes Rickman C
Scientific reports 2017 Jul 7;7(1):4901
Scientific reports 2017 Jul 7;7(1):4901
Matrix stiffening promotes a tumor vasculature phenotype.
Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA
Proceedings of the National Academy of Sciences of the United States of America 2017 Jan 17;114(3):492-497
Proceedings of the National Academy of Sciences of the United States of America 2017 Jan 17;114(3):492-497
mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis.
Foerster P, Daclin M, Asm S, Faucourt M, Boletta A, Genovesio A, Spassky N
Development (Cambridge, England) 2017 Jan 15;144(2):201-210
Development (Cambridge, England) 2017 Jan 15;144(2):201-210
Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium.
Zhang W, Li H, Ogando DG, Li S, Feng M, Price FW Jr, Tennessen JM, Bonanno JA
EBioMedicine 2017 Feb;16:292-301
EBioMedicine 2017 Feb;16:292-301
Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model.
Miyashita H, Niwano H, Yoshida S, Hatou S, Inagaki E, Tsubota K, Shimmura S
Scientific reports 2017 Feb 24;7:43557
Scientific reports 2017 Feb 24;7:43557
Effects of HIV-1 Tat and Methamphetamine on Blood-Brain Barrier Integrity and Function In Vitro.
Patel S, Leibrand CR, Palasuberniam P, Couraud PO, Weksler B, Jahr FM, McClay JL, Hauser KF, McRae M
Antimicrobial agents and chemotherapy 2017 Dec;61(12)
Antimicrobial agents and chemotherapy 2017 Dec;61(12)
The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
Pelz L, Purfürst B, Rathjen FG
The Journal of biological chemistry 2017 Dec 29;292(52):21490-21503
The Journal of biological chemistry 2017 Dec 29;292(52):21490-21503
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry.
Kearns VR, Tasker J, Zhuola, Akhtar R, Bachhuka A, Vasilev K, Sheridan CM, Williams RL
Journal of materials science. Materials in medicine 2017 Aug;28(8):124
Journal of materials science. Materials in medicine 2017 Aug;28(8):124
Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity.
Prasad S, Sajja RK, Kaisar MA, Park JH, Villalba H, Liles T, Abbruscato T, Cucullo L
Redox biology 2017 Aug;12:58-69
Redox biology 2017 Aug;12:58-69
Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs).
DeStefano JG, Xu ZS, Williams AJ, Yimam N, Searson PC
Fluids and barriers of the CNS 2017 Aug 4;14(1):20
Fluids and barriers of the CNS 2017 Aug 4;14(1):20
A new strategy to measure intercellular adhesion forces in mature cell-cell contacts.
Sancho A, Vandersmissen I, Craps S, Luttun A, Groll J
Scientific reports 2017 Apr 10;7:46152
Scientific reports 2017 Apr 10;7:46152
Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane.
Soayfane Z, Tercé F, Cantiello M, Robenek H, Nauze M, Bézirard V, Allart S, Payré B, Capilla F, Cartier C, Peres C, Al Saati T, Théodorou V, Nelson DW, Yen CE, Collet X, Coméra C
Nutrition & metabolism 2016;13:48
Nutrition & metabolism 2016;13:48
Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum.
Dauleh S, Santeramo I, Fielding C, Ward K, Herrmann A, Murray P, Wilm B
PloS one 2016;11(7):e0158997
PloS one 2016;11(7):e0158997
Cerebral Apolipoprotein-D Is Hypoglycosylated Compared to Peripheral Tissues and Is Variably Expressed in Mouse and Human Brain Regions.
Li H, Ruberu K, Karl T, Garner B
PloS one 2016;11(2):e0148238
PloS one 2016;11(2):e0148238
A2A Adenosine Receptor Antagonism Reverts the Blood-Brain Barrier Dysfunction Induced by Sleep Restriction.
Hurtado-Alvarado G, Domínguez-Salazar E, Velázquez-Moctezuma J, Gómez-González B
PloS one 2016;11(11):e0167236
PloS one 2016;11(11):e0167236
The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.
Waisbourd-Zinman O, Koh H, Tsai S, Lavrut PM, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG
Hepatology (Baltimore, Md.) 2016 Sep;64(3):880-93
Hepatology (Baltimore, Md.) 2016 Sep;64(3):880-93
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity.
Chen B, Zheng B, DeRan M, Jarugumilli GK, Fu J, Brooks YS, Wu X
Nature chemical biology 2016 Sep;12(9):686-93
Nature chemical biology 2016 Sep;12(9):686-93
Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice.
Xiong J, Zhou MF, Wang YD, Chen LP, Xu WF, Wang YD, Deng F, Liu SD
Scientific reports 2016 Sep 23;6:34079
Scientific reports 2016 Sep 23;6:34079
HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its Permeability.
Qian YW, Li C, Jiang AP, Ge S, Gu P, Fan X, Li TS, Jin X, Wang JH, Wang ZL
The Journal of biological chemistry 2016 Oct 28;291(44):22977-22987
The Journal of biological chemistry 2016 Oct 28;291(44):22977-22987
Hypertonic saline alleviates experimentally induced cerebral oedema through suppression of vascular endothelial growth factor and its receptor VEGFR2 expression in astrocytes.
Huang L, Cao W, Deng Y, Zhu G, Han Y, Zeng H
BMC neuroscience 2016 Oct 13;17(1):64
BMC neuroscience 2016 Oct 13;17(1):64
Quantification of Confocal Images Using LabVIEW for Tissue Engineering Applications.
Sfakis L, Kamaldinov T, Larsen M, Castracane J, Khmaladze A
Tissue engineering. Part C, Methods 2016 Nov;22(11):1028-1037
Tissue engineering. Part C, Methods 2016 Nov;22(11):1028-1037
Δ(9)-Tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB(2) receptors.
Shang VC, Kendall DA, Roberts RE
Biochemical pharmacology 2016 Nov 15;120:63-71
Biochemical pharmacology 2016 Nov 15;120:63-71
An in vitro model of murine middle ear epithelium.
Mulay A, Akram KM, Williams D, Armes H, Russell C, Hood D, Armstrong S, Stewart JP, Brown SD, Bingle L, Bingle CD
Disease models & mechanisms 2016 Nov 1;9(11):1405-1417
Disease models & mechanisms 2016 Nov 1;9(11):1405-1417
PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position.
Luján P, Varsano G, Rubio T, Hennrich ML, Sachsenheimer T, Gálvez-Santisteban M, Martín-Belmonte F, Gavin AC, Brügger B, Köhn M
Journal of cell science 2016 Nov 1;129(21):4130-4142
Journal of cell science 2016 Nov 1;129(21):4130-4142
Epithelial cell lines of the cotton rat (Sigmodon hispidus) are highly susceptible in vitro models to zoonotic Bunya-, Rhabdo-, and Flaviviruses.
Ehlen L, Tödtmann J, Specht S, Kallies R, Papies J, Müller MA, Junglen S, Drosten C, Eckerle I
Virology journal 2016 May 4;13:74
Virology journal 2016 May 4;13:74
Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon.
Lee SY, Kim H, Kim K, Lee H, Lee S, Lee D
Scientific reports 2016 May 27;6:26923
Scientific reports 2016 May 27;6:26923
Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells.
Stebbins MJ, Wilson HK, Canfield SG, Qian T, Palecek SP, Shusta EV
Methods (San Diego, Calif.) 2016 May 15;101:93-102
Methods (San Diego, Calif.) 2016 May 15;101:93-102
Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown.
Xu S, Xue X, You K, Fu J
Respiratory research 2016 May 12;17(1):50
Respiratory research 2016 May 12;17(1):50
Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism.
Yamaura Y, Chapron BD, Wang Z, Himmelfarb J, Thummel KE
Drug metabolism and disposition: the biological fate of chemicals 2016 Mar;44(3):329-35
Drug metabolism and disposition: the biological fate of chemicals 2016 Mar;44(3):329-35
The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite.
Shang VC, O'Sullivan SE, Kendall DA, Roberts RE
Pharmacological research 2016 Mar;105:152-63
Pharmacological research 2016 Mar;105:152-63
Dynamics of BMP and Hes1/Hairy1 signaling in the dorsal neural tube underlies the transition from neural crest to definitive roof plate.
Nitzan E, Avraham O, Kahane N, Ofek S, Kumar D, Kalcheim C
BMC biology 2016 Mar 24;14:23
BMC biology 2016 Mar 24;14:23
Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells.
Bassey-Archibong BI, Kwiecien JM, Milosavljevic SB, Hallett RM, Rayner LG, Erb MJ, Crawford-Brown CJ, Stephenson KB, Bédard PA, Hassell JA, Daniel JM
Oncogenesis 2016 Mar 21;5(3):e208
Oncogenesis 2016 Mar 21;5(3):e208
Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration.
Trembley MA, Velasquez LS, Small EM
Journal of visualized experiments : JoVE 2016 Mar 18;(109)
Journal of visualized experiments : JoVE 2016 Mar 18;(109)
Leukocyte Infiltration Triggers Seizure Recurrence in a Rat Model of Temporal Lobe Epilepsy.
Liu Z, Wang S, Liu J, Wang F, Liu Y, Zhao Y
Inflammation 2016 Jun;39(3):1090-8
Inflammation 2016 Jun;39(3):1090-8
GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells.
Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Fischer S, Rodriguez VM, Otte K, Velagapudi V, Toppari J, Wilson DB, Heikinheimo M
Endocrinology 2016 Jun;157(6):2416-31
Endocrinology 2016 Jun;157(6):2416-31
CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis.
Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, Richter JD
Oncogene 2016 Jun 2;35(22):2893-901
Oncogene 2016 Jun 2;35(22):2893-901
Connexin 50 Regulates Surface Ball-and-Socket Structures and Fiber Cell Organization.
Wang E, Geng A, Maniar AM, Mui BW, Gong X
Investigative ophthalmology & visual science 2016 Jun 1;57(7):3039-46
Investigative ophthalmology & visual science 2016 Jun 1;57(7):3039-46
Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.
Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D
American journal of physiology. Gastrointestinal and liver physiology 2016 Jun 1;310(11):G1124-37
American journal of physiology. Gastrointestinal and liver physiology 2016 Jun 1;310(11):G1124-37
Intestinal barrier analysis by assessment of mucins, tight junctions, and α-defensins in healthy C57BL/6J and BALB/cJ mice.
Volynets V, Rings A, Bárdos G, Ostaff MJ, Wehkamp J, Bischoff SC
Tissue barriers 2016 Jul-Sep;4(3):e1208468
Tissue barriers 2016 Jul-Sep;4(3):e1208468
3D map of the human corneal endothelial cell.
He Z, Forest F, Gain P, Rageade D, Bernard A, Acquart S, Peoc'h M, Defoe DM, Thuret G
Scientific reports 2016 Jul 6;6:29047
Scientific reports 2016 Jul 6;6:29047
Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling.
Guo YH, Wang LQ, Li B, Xu H, Yang JH, Zheng LS, Yu P, Zhou AD, Zhang Y, Xie SJ, Liang ZR, Zhang CM, Zhou H, Qu LH
Oncotarget 2016 Jul 5;7(27):42513-42526
Oncotarget 2016 Jul 5;7(27):42513-42526
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
Souma T, Tompson SW, Thomson BR, Siggs OM, Kizhatil K, Yamaguchi S, Feng L, Limviphuvadh V, Whisenhunt KN, Maurer-Stroh S, Yanovitch TL, Kalaydjieva L, Azmanov DN, Finzi S, Mauri L, Javadiyan S, Souzeau E, Zhou T, Hewitt AW, Kloss B, Burdon KP, Mackey DA, Allen KF, Ruddle JB, Lim SH, Rozen S, Tran-Viet KN, Liu X, John S, Wiggs JL, Pasutto F, Craig JE, Jin J, Quaggin SE, Young TL
The Journal of clinical investigation 2016 Jul 1;126(7):2575-87
The Journal of clinical investigation 2016 Jul 1;126(7):2575-87
Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction.
Loebel DA, Plageman TF Jr, Tang TL, Jones VJ, Muccioli M, Tam PP
Biology open 2016 Jan 15;5(2):130-9
Biology open 2016 Jan 15;5(2):130-9
Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration.
Ibrahim AS, Mander S, Hussein KA, Elsherbiny NM, Smith SB, Al-Shabrawey M, Tawfik A
Oncotarget 2016 Feb 23;7(8):8532-45
Oncotarget 2016 Feb 23;7(8):8532-45
High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells.
Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, Feng J, Hong H, Qi W, Ma C, Wu Q, Yang X, Gao G
International journal of molecular medicine 2016 Dec;38(6):1815-1822
International journal of molecular medicine 2016 Dec;38(6):1815-1822
Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.
Iwai-Takekoshi L, Ramos A, Schaler A, Weinreb S, Blazeski R, Mason C
The Journal of comparative neurology 2016 Dec 15;524(18):3696-3716
The Journal of comparative neurology 2016 Dec 15;524(18):3696-3716
Cutting and Decellularization of Multiple Corneal Stromal Lamellae for the Bioengineering of Endothelial Grafts.
He Z, Forest F, Bernard A, Gauthier AS, Montard R, Peoc'h M, Jumelle C, Courrier E, Perrache C, Gain P, Thuret G
Investigative ophthalmology & visual science 2016 Dec 1;57(15):6639-6651
Investigative ophthalmology & visual science 2016 Dec 1;57(15):6639-6651
Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption.
Wang X, Fan F, Cao Q
Molecular medicine reports 2016 Aug;14(2):1173-9
Molecular medicine reports 2016 Aug;14(2):1173-9
In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart.
Ramesh S, Singh A, Cibi DM, Hausenloy DJ, Singh MK
Journal of visualized experiments : JoVE 2016 Apr 27;(110)
Journal of visualized experiments : JoVE 2016 Apr 27;(110)
Features specific to retinal pigment epithelium cells derived from three-dimensional human embryonic stem cell cultures - a new donor for cell therapy.
Wu W, Zeng Y, Li Z, Li Q, Xu H, Yin ZQ
Oncotarget 2016 Apr 19;7(16):22819-33
Oncotarget 2016 Apr 19;7(16):22819-33
NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration.
Viringipurampeer IA, Metcalfe AL, Bashar AE, Sivak O, Yanai A, Mohammadi Z, Moritz OL, Gregory-Evans CY, Gregory-Evans K
Human molecular genetics 2016 Apr 15;25(8):1501-16
Human molecular genetics 2016 Apr 15;25(8):1501-16
Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons.
Straccia M, Garcia-Diaz Barriga G, Sanders P, Bombau G, Carrere J, Mairal PB, Vinh NN, Yung S, Kelly CM, Svendsen CN, Kemp PJ, Arjomand J, Schoenfeld RC, Alberch J, Allen ND, Rosser AE, Canals JM
Molecular therapy. Methods & clinical development 2015;2:15030
Molecular therapy. Methods & clinical development 2015;2:15030
Annexin A3 Regulates Early Blood Vessel Formation.
Meadows SM, Cleaver O
PloS one 2015;10(7):e0132580
PloS one 2015;10(7):e0132580
Junctional abnormalities in human airway epithelial cells expressing F508del CFTR.
Molina SA, Stauffer B, Moriarty HK, Kim AH, McCarty NA, Koval M
American journal of physiology. Lung cellular and molecular physiology 2015 Sep 1;309(5):L475-87
American journal of physiology. Lung cellular and molecular physiology 2015 Sep 1;309(5):L475-87
Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice.
Li CH, Shyu MK, Jhan C, Cheng YW, Tsai CH, Liu CW, Lee CC, Chen RM, Kang JJ
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):192-203
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):192-203
Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing.
Coulson-Thomas VJ, Chang SH, Yeh LK, Coulson-Thomas YM, Yamaguchi Y, Esko J, Liu CY, Kao W
Investigative ophthalmology & visual science 2015 May;56(5):3004-14
Investigative ophthalmology & visual science 2015 May;56(5):3004-14
17β-estradiol inhibits MMP-9 and SUR1/TrpM4 expression and activation and thereby attenuates BSCB disruption/hemorrhage after spinal cord injury in male rats.
Lee JY, Choi HY, Na WH, Ju BG, Yune TY
Endocrinology 2015 May;156(5):1838-50
Endocrinology 2015 May;156(5):1838-50
Effect of differentiation on endocytic profiles of endothelial and epithelial cell culture models.
Ilina P, Partti S, Niklander J, Ruponen M, Lou YR, Yliperttula M
Experimental cell research 2015 Mar 1;332(1):89-101
Experimental cell research 2015 Mar 1;332(1):89-101
Regulation of age-related macular degeneration-like pathology by complement factor H.
Toomey CB, Kelly U, Saban DR, Bowes Rickman C
Proceedings of the National Academy of Sciences of the United States of America 2015 Jun 9;112(23):E3040-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Jun 9;112(23):E3040-9
Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells.
Cong X, Zhang Y, Li J, Mei M, Ding C, Xiang RL, Zhang LW, Wang Y, Wu LL, Yu GY
Journal of cell science 2015 Jun 15;128(12):2271-86
Journal of cell science 2015 Jun 15;128(12):2271-86
The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.
Kim S, Lahmy R, Riha C, Yang C, Jakubison BL, van Niekerk J, Staub C, Wu Y, Gates K, Dong DS, Konieczny SF, Itkin-Ansari P
Pancreas 2015 Jul;44(5):718-27
Pancreas 2015 Jul;44(5):718-27
The Polarity Protein Pals1 Regulates Radial Sorting of Axons.
Zollinger DR, Chang KJ, Baalman K, Kim S, Rasband MN
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Jul 22;35(29):10474-84
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Jul 22;35(29):10474-84
FGF8 coordinates tissue elongation and cell epithelialization during early kidney tubulogenesis.
Atsuta Y, Takahashi Y
Development (Cambridge, England) 2015 Jul 1;142(13):2329-37
Development (Cambridge, England) 2015 Jul 1;142(13):2329-37
Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers.
Watari A, Hashegawa M, Yagi K, Kondoh M
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2015 Jan;89:232-8
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2015 Jan;89:232-8
The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye.
López-Escobar B, Cano DA, Rojas A, de Felipe B, Palma F, Sánchez-Alcázar JA, Henderson D, Ybot-González P
Disease models & mechanisms 2015 Feb;8(2):157-68
Disease models & mechanisms 2015 Feb;8(2):157-68
ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer.
Griner NB, Young D, Chaudhary P, Mohamed AA, Huang W, Chen Y, Sreenath T, Dobi A, Petrovics G, Vishwanatha JK, Sesterhenn IA, Srivastava S, Tan SH
Molecular cancer research : MCR 2015 Feb;13(2):368-79
Molecular cancer research : MCR 2015 Feb;13(2):368-79
Human Alpha-Defensin HNP1 Increases HIV Traversal of the Epithelial Barrier: A Potential Role in STI-Mediated Enhancement of HIV Transmission.
Valere K, Rapista A, Eugenin E, Lu W, Chang TL
Viral immunology 2015 Dec;28(10):609-15
Viral immunology 2015 Dec;28(10):609-15
Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E.
Smith KA, Zhou B, Avdulov S, Benyumov A, Peterson M, Liu Y, Okon A, Hergert P, Braziunas J, Wagner CR, Borok Z, Bitterman PB
Scientific reports 2015 Dec 18;5:18233
Scientific reports 2015 Dec 18;5:18233
Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa.
Goichon A, Bertrand J, Chan P, Lecleire S, Coquard A, Cailleux AF, Vaudry D, Déchelotte P, Coëffier M
The American journal of clinical nutrition 2015 Aug;102(2):359-67
The American journal of clinical nutrition 2015 Aug;102(2):359-67
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
Liu KM, Chuang SM, Long CY, Lee YL, Wang CC, Lu MC, Lin RJ, Lu JH, Jang MY, Wu WJ, Ho WT, Juan YS
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells.
Chou CH, Sinden JD, Couraud PO, Modo M
PloS one 2014;9(9):e106346
PloS one 2014;9(9):e106346
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration.
Morganti JM, Jopson TD, Liu S, Gupta N, Rosi S
PloS one 2014;9(4):e93650
PloS one 2014;9(4):e93650
In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.
Berkenkamp B, Susnik N, Baisantry A, Kuznetsova I, Jacobi C, Sörensen-Zender I, Broecker V, Haller H, Melk A, Schmitt R
PloS one 2014;9(2):e88071
PloS one 2014;9(2):e88071
Bat airway epithelial cells: a novel tool for the study of zoonotic viruses.
Eckerle I, Ehlen L, Kallies R, Wollny R, Corman VM, Cottontail VM, Tschapka M, Oppong S, Drosten C, Müller MA
PloS one 2014;9(1):e84679
PloS one 2014;9(1):e84679
Delayed near-infrared analysis permits visualization of rodent retinal pigment epithelium layer in vivo.
Pankova N, Zhao X, Liang H, Baek DS, Wang H, Boyd S
Journal of biomedical optics 2014;19(7):076007
Journal of biomedical optics 2014;19(7):076007
Gene therapy in patient-specific stem cell lines and a preclinical model of retinitis pigmentosa with membrane frizzled-related protein defects.
Li Y, Wu WH, Hsu CW, Nguyen HV, Tsai YT, Chan L, Nagasaki T, Maumenee IH, Yannuzzi LA, Hoang QV, Hua H, Egli D, Tsang SH
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Sep;22(9):1688-97
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Sep;22(9):1688-97
MAGI-2 is critical for the formation and maintenance of the glomerular filtration barrier in mouse kidney.
Ihara K, Asanuma K, Fukuda T, Ohwada S, Yoshida M, Nishimori K
The American journal of pathology 2014 Oct;184(10):2699-708
The American journal of pathology 2014 Oct;184(10):2699-708
MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells.
Formosa A, Markert EK, Lena AM, Italiano D, Finazzi-Agro' E, Levine AJ, Bernardini S, Garabadgiu AV, Melino G, Candi E
Oncogene 2014 Oct 30;33(44):5173-82
Oncogene 2014 Oct 30;33(44):5173-82
Polymeric nanocarriers for transport modulation across the pulmonary epithelium: dendrimers, polymeric nanoparticles, and their nanoblends.
Bharatwaj B, Dimovski R, Conti DS, da Rocha SR
The AAPS journal 2014 May;16(3):522-38
The AAPS journal 2014 May;16(3):522-38
Mast cells protect against Pseudomonas aeruginosa-induced lung injury.
Junkins RD, Carrigan SO, Wu Z, Stadnyk AW, Cowley E, Issekutz T, Berman J, Lin TJ
The American journal of pathology 2014 Aug;184(8):2310-21
The American journal of pathology 2014 Aug;184(8):2310-21
Effect of retinoic acid on the tight junctions of the retinal pigment epithelium-choroid complex of guinea pigs with lens-induced myopia in vivo.
Wang S, Liu S, Mao J, Wen D
International journal of molecular medicine 2014 Apr;33(4):825-32
International journal of molecular medicine 2014 Apr;33(4):825-32
Notch signaling maintains neural rosette polarity.
Main H, Radenkovic J, Jin SB, Lendahl U, Andersson ER
PloS one 2013;8(5):e62959
PloS one 2013;8(5):e62959
Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth.
Baker M, Reynolds LE, Robinson SD, Lees DM, Parsons M, Elia G, Hodivala-Dilke K
PloS one 2013;8(5):e62516
PloS one 2013;8(5):e62516
Histopathological, immunohistochemical criteria and confocal laser-scanning data of arthrofibrosis.
Ruppert M, Theiss C, Knöß P, Kendoff D, Krukemeyer MG, Schröder N, Brand-Saberi B, Gehrke T, Krenn V
Pathology, research and practice 2013 Nov;209(11):681-8
Pathology, research and practice 2013 Nov;209(11):681-8
A2E accumulation influences retinal microglial activation and complement regulation.
Ma W, Coon S, Zhao L, Fariss RN, Wong WT
Neurobiology of aging 2013 Mar;34(3):943-60
Neurobiology of aging 2013 Mar;34(3):943-60
Apical sorting of lysoGPI-anchored proteins occurs independent of association with detergent-resistant membranes but dependent on their N-glycosylation.
Castillon GA, Michon L, Watanabe R
Molecular biology of the cell 2013 Jun;24(12):2021-33
Molecular biology of the cell 2013 Jun;24(12):2021-33
Corneal endothelial cell fate is maintained by LGR5 through the regulation of hedgehog and Wnt pathway.
Hirata-Tominaga K, Nakamura T, Okumura N, Kawasaki S, Kay EP, Barrandon Y, Koizumi N, Kinoshita S
Stem cells (Dayton, Ohio) 2013 Jul;31(7):1396-407
Stem cells (Dayton, Ohio) 2013 Jul;31(7):1396-407
Small molecule mediated proliferation of primary retinal pigment epithelial cells.
Swoboda JG, Elliott J, Deshmukh V, de Lichtervelde L, Shen W, Tremblay MS, Peters EC, Cho CY, Lu B, Girman S, Wang S, Schultz PG
ACS chemical biology 2013 Jul 19;8(7):1407-11
ACS chemical biology 2013 Jul 19;8(7):1407-11
Lumican expression, localization and antitumor activity in prostate cancer.
Coulson-Thomas VJ, Coulson-Thomas YM, Gesteira TF, Andrade de Paula CA, Carneiro CR, Ortiz V, Toma L, Kao WW, Nader HB
Experimental cell research 2013 Apr 15;319(7):967-81
Experimental cell research 2013 Apr 15;319(7):967-81
Unique cell type-specific junctional complexes in vascular endothelium of human and rat liver sinusoids.
Géraud C, Evdokimov K, Straub BK, Peitsch WK, Demory A, Dörflinger Y, Schledzewski K, Schmieder A, Schemmer P, Augustin HG, Schirmacher P, Goerdt S
PloS one 2012;7(4):e34206
PloS one 2012;7(4):e34206
Defects in the outer limiting membrane are associated with rosette development in the Nrl-/- retina.
Stuck MW, Conley SM, Naash MI
PloS one 2012;7(3):e32484
PloS one 2012;7(3):e32484
CD40-activated B cells can efficiently prime antigen-specific naïve CD8+ T cells to generate effector but not memory T cells.
Mathieu M, Cotta-Grand N, Daudelin JF, Boulet S, Lapointe R, Labrecque N
PloS one 2012;7(1):e30139
PloS one 2012;7(1):e30139
Distinct distribution of the tensin family in the mouse kidney and small intestine.
Nishino T, Sasaki N, Chihara M, Nagasaki K, Torigoe D, Kon Y, Agui T
Experimental animals 2012;61(5):525-32
Experimental animals 2012;61(5):525-32
Identification of new binding partners of the chemosensory signaling protein Gγ13 expressed in taste and olfactory sensory cells.
Liu Z, Fenech C, Cadiou H, Grall S, Tili E, Laugerette F, Wiencis A, Grosmaitre X, Montmayeur JP
Frontiers in cellular neuroscience 2012;6:26
Frontiers in cellular neuroscience 2012;6:26
Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research.
Stewart CE, Torr EE, Mohd Jamili NH, Bosquillon C, Sayers I
Journal of allergy 2012;2012:943982
Journal of allergy 2012;2012:943982
Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).
Zhou B, Liu Y, Kahn M, Ann DK, Han A, Wang H, Nguyen C, Flodby P, Zhong Q, Krishnaveni MS, Liebler JM, Minoo P, Crandall ED, Borok Z
The Journal of biological chemistry 2012 Mar 2;287(10):7026-38
The Journal of biological chemistry 2012 Mar 2;287(10):7026-38
Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis.
Harrelson Z, Kaestner KH, Evans SM
Biology open 2012 Mar 15;1(3):173-81
Biology open 2012 Mar 15;1(3):173-81
Redistribution of adhering junctions in human endometrial epithelial cells during the implantation window of the menstrual cycle.
Buck VU, Windoffer R, Leube RE, Classen-Linke I
Histochemistry and cell biology 2012 Jun;137(6):777-90
Histochemistry and cell biology 2012 Jun;137(6):777-90
HIF-1 is involved in high glucose-induced paracellular permeability of brain endothelial cells.
Yan J, Zhang Z, Shi H
Cellular and molecular life sciences : CMLS 2012 Jan;69(1):115-28
Cellular and molecular life sciences : CMLS 2012 Jan;69(1):115-28
Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa.
Li Y, Tsai YT, Hsu CW, Erol D, Yang J, Wu WH, Davis RJ, Egli D, Tsang SH
Molecular medicine (Cambridge, Mass.) 2012 Dec 6;18(1):1312-9
Molecular medicine (Cambridge, Mass.) 2012 Dec 6;18(1):1312-9
Extracellular matrix assembly and 3D organization during paraxial mesoderm development in the chick embryo.
Rifes P, Thorsteinsdóttir S
Developmental biology 2012 Aug 15;368(2):370-81
Developmental biology 2012 Aug 15;368(2):370-81
Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts.
Ott C, Elia N, Jeong SY, Insinna C, Sengupta P, Lippincott-Schwartz J
Cilia 2012 Apr 25;1(1):3
Cilia 2012 Apr 25;1(1):3
Dynamics of claudins expression in colitis and colitis-associated cancer in rat.
Arimura Y, Nagaishi K, Hosokawa M
Methods in molecular biology (Clifton, N.J.) 2011;762:409-25
Methods in molecular biology (Clifton, N.J.) 2011;762:409-25
The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro.
Bray K, Brakebusch C, Vargo-Gogola T
Small GTPases 2011 Sep;2(5):247-258
Small GTPases 2011 Sep;2(5):247-258
Cell culture models using rat primary alveolar type I cells.
Downs CA, Montgomery DW, Merkle CJ
Pulmonary pharmacology & therapeutics 2011 Oct;24(5):577-86
Pulmonary pharmacology & therapeutics 2011 Oct;24(5):577-86
Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endoderm.
Loebel DA, Studdert JB, Power M, Radziewic T, Jones V, Coultas L, Jackson Y, Rao RS, Steiner K, Fossat N, Robb L, Tam PP
Development (Cambridge, England) 2011 Oct;138(20):4511-22
Development (Cambridge, England) 2011 Oct;138(20):4511-22
LGN-dependent orientation of cell divisions in the dermomyotome controls lineage segregation into muscle and dermis.
Ben-Yair R, Kahane N, Kalcheim C
Development (Cambridge, England) 2011 Oct;138(19):4155-66
Development (Cambridge, England) 2011 Oct;138(19):4155-66
MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development.
Singh MK, Lu MM, Massera D, Epstein JA
The Journal of biological chemistry 2011 Nov 25;286(47):41036-45
The Journal of biological chemistry 2011 Nov 25;286(47):41036-45
N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct.
Sproul A, Steele SL, Thai TL, Yu S, Klein JD, Sands JM, Bell PD
American journal of physiology. Renal physiology 2011 Jul;301(1):F44-54
American journal of physiology. Renal physiology 2011 Jul;301(1):F44-54
Secondary neurulation: Fate-mapping and gene manipulation of the neural tube in tail bud.
Shimokita E, Takahashi Y
Development, growth & differentiation 2011 Apr;53(3):401-10
Development, growth & differentiation 2011 Apr;53(3):401-10
The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.
Müller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E
Development (Cambridge, England) 2011 Apr;138(7):1297-308
Development (Cambridge, England) 2011 Apr;138(7):1297-308
Correlating cell behavior with tissue topology in embryonic epithelia.
Sandersius SA, Chuai M, Weijer CJ, Newman TJ
PloS one 2011 Apr 29;6(4):e18081
PloS one 2011 Apr 29;6(4):e18081
Selective ablation of the androgen receptor in mouse sertoli cells affects sertoli cell maturation, barrier formation and cytoskeletal development.
Willems A, Batlouni SR, Esnal A, Swinnen JV, Saunders PT, Sharpe RM, França LR, De Gendt K, Verhoeven G
PloS one 2010 Nov 30;5(11):e14168
PloS one 2010 Nov 30;5(11):e14168
A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells.
Ferrell N, Desai RR, Fleischman AJ, Roy S, Humes HD, Fissell WH
Biotechnology and bioengineering 2010 Nov 1;107(4):707-16
Biotechnology and bioengineering 2010 Nov 1;107(4):707-16
Microscopic mammalian retinal pigment epithelium lesions induce widespread proliferation with differences in magnitude between center and periphery.
von Leithner PL, Ciurtin C, Jeffery G
Molecular vision 2010 Mar 31;16:570-81
Molecular vision 2010 Mar 31;16:570-81
Acute and chronic deficits in the urinary bladder after spinal contusion injury in the adult rat.
Herrera JJ, Haywood-Watson RJ 2nd, Grill RJ
Journal of neurotrauma 2010 Feb;27(2):423-31
Journal of neurotrauma 2010 Feb;27(2):423-31
Ultrastructure and regulation of lateralized connexin43 in the failing heart.
Hesketh GG, Shah MH, Halperin VL, Cooke CA, Akar FG, Yen TE, Kass DA, Machamer CE, Van Eyk JE, Tomaselli GF
Circulation research 2010 Apr 2;106(6):1153-63
Circulation research 2010 Apr 2;106(6):1153-63
Molecular staging of epithelial maturation using secretory cell-specific genes as markers.
Zemke AC, Snyder JC, Brockway BL, Drake JA, Reynolds SD, Kaminski N, Stripp BR
American journal of respiratory cell and molecular biology 2009 Mar;40(3):340-8
American journal of respiratory cell and molecular biology 2009 Mar;40(3):340-8
RhoA and microtubule dynamics control cell-basement membrane interaction in EMT during gastrulation.
Nakaya Y, Sukowati EW, Wu Y, Sheng G
Nature cell biology 2008 Jul;10(7):765-75
Nature cell biology 2008 Jul;10(7):765-75
Functionally specialized junctions between endothelial cells of lymphatic vessels.
Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, Butz S, Vestweber D, Corada M, Molendini C, Dejana E, McDonald DM
The Journal of experimental medicine 2007 Oct 1;204(10):2349-62
The Journal of experimental medicine 2007 Oct 1;204(10):2349-62
Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium.
Daniele LL, Adams RH, Durante DE, Pugh EN Jr, Philp NJ
The Journal of comparative neurology 2007 Nov 10;505(2):166-76
The Journal of comparative neurology 2007 Nov 10;505(2):166-76
ZO-1 is required for protein kinase C gamma-driven disassembly of connexin 43.
Akoyev V, Takemoto DJ
Cellular signalling 2007 May;19(5):958-67
Cellular signalling 2007 May;19(5):958-67
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
Penes MC, Li X, Nagy JI
The European journal of neuroscience 2005 Jul;22(2):404-18
The European journal of neuroscience 2005 Jul;22(2):404-18
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- Western blot analysis of (A) MDCKII, (B) A431, (C) Caco-2, (D) Rat-1, and (E) NRK-52E cell lysates using Rb anti-ZO-1 (Mid) (Product # 40-2200).
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- Immunofluorescent staining of Caco-2 cells using Rb anti-ZO-1 (Mid) (Product # 40-2200). Image courtesy of Jacey Bennis and Dr. James Anderson, University of North Carolina at Chapel Hill, NC.
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- Indirect immunofluorescence staining of MDCKII cells using Zymed Rb anti-ZO-1 (Mid) (Product # 40-2200). Image courtesy of Jacey Bennis and Dr. James Anderson, University of North Carolina at Chapel Hill, NC.
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- Indirect immunofluorescence staining of Caco-2 cells using Rb anti-ZO-1 (Mid). (PAD: ZMD.436) (Product # 40-2200 (green), and anti-Occludin (red). Co-localization is in yellow. Image courtesy of Jacey Bennis and Dr. James Anderson, University of North Carolina at Chapel Hill, NC.
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- Immunofluorescent detection of Zo-1 in MDCK cells. Confluent monolayers were fixed in 50%methanol/50%Acetone, blocked for at least 30 minutes in 1% BSA then incubated 2 hours with a Zo-1 rabbit polyclonal antibody (Product # 40-2200) at 2.5 µg/mL, washed, then incubated 1 hour with Alexa Fluor 488 conjugated Donkey anti-Rabbit secondary antibody (Product # A-21206) at 1:2000 dilution. Cells were counterstained with DAPI (blue). Coverslips were mounted with Prolong Gold Antifade reagent (Product # P36930) and imaged at 40X. Images generated by Joell Solan in Paul Lampe Lab at the Fred Hutchinson cancer Research Center.
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- Immunofluorescence analysis of ZO-1 was performed using 90% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with ZO-1 Polyclonal Antibody (Product # 40-2200) at 5 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790), (1:2000 dilution), for 45 minutes at room temperature (Panel a: Green). Nuclei (Panel b:Blue) were stained with ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962). F-actin (Panel c: Red) was stained with Rhodamine Phalloidin (Product # R415, 1:300 dilution). Panel d represents the merged image showing Junctional localization. Panel e represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.
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- Immunofluorescence analysis of ZO-1 was performed using 90% confluent log phase Caco-2 IFN Gamma (50 ng/mL for 24hrs). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with ZO-1 Polyclonal Antibody (Product # 40-2200) at 5 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790), (1:2000), for 45 minutes at room temperature (Panel a: Green). Nuclei (Panel b:Blue) were stained with ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962). F-actin (Panel c: Red) was stained with Rhodamine Phalloidin (Product # R415, 1:300). Panel d represents the merged image showing Junction localization. Panel e represents downregulation upon treatment Panel f represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.
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- Knockdown of ZO-1 was achieved by transfecting Caco-2 cells with ZO-1 specific siRNA (Silencer® select Product # s14155, s14156). Immunofluorescence analysis was performed on untransfected Caco-2 cells (panel a-d), transfected with non-specific scrambled siRNA (panels e-h) and transfected with ZO-1 specific siRNA (panel i-l). Cells were fixed, permeabilized, and labelled with ZO-1 Polyclonal Antibody (Product # 40-2200, 5 µg/mL) followed by Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790), (1:2000 dilution). Nuclei (blue) were stained using ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962), and Rhodamine Phalloidin (Product # R415, 1:300 dilution) was used for cytoskeletal F-actin (Red) staining. Partial reduction in signal of specific signal was observed upon siRNA mediated knockdown (panel i-l) confirming specificity of the antibody to ZO-1 (Green). The Images were captured at 60X magnification.
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- Immunofluorescent staining of mouse liver tissue using Rb anti-ZO-1 (Mid) (Product # 40-2200). Image courtesy of James I. Nagy, PhD, University of Manitoba, Canada.
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- Immunofluorescent staining of mouse brain mosssy fiber terminals using Rb anti-ZO-1 (Mid) (Product # 40-2200). Image courtesy of James I. Nagy, PhD, University of Manitoba, Canada.
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- Immunofluorescent staining of blood vessels in mouse heart tissue using Rb anti-ZO-1 (Mid) (Product # 40-2200). Image courtesy of James I. Nagy, PhD, University of Manitoba, Canada.
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- Immunofluorescent staining of mouse liver tissue using Rb anti-ZO-1 (Mid) (Product # 40-2200). Image courtesy of James I. Nagy, PhD, University of Manitoba, Canada.
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- Figure 8 rEhCP112p binds to claudin-1 and claudin-2. Confluent Caco-2 cell monolayers were incubated for 10 min with rEhCP112p, then, cell lysates were immunoprecipitated (IP) in the presence of protease inhibitors, using alpha-EhCP112 antibody or pre-immune serum (PS). Immunoprecipitates, rEhCP112p and Caco-2 cell lysates (Caco-2) were submitted to WB assays and revealed using the antibodies indicated at left.
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- Fig. 8 Representative immunofluorescence images of dhBMEC monolayers fixed and stained after 40 h at 0, 4, and 12 dyne cm -2 . a , e , i CLDN-5. b , f , j OCLN. c , g , k ZO-1. d , h , l F-actin. Note that CLDN-5/OCLN and ZO-1/f-actin were obtained for different monolayers
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- Figure 5 ZO-1 and ZO-2 localize to VE-cadherin-containing cell-cell junctions in rat liver sinusoidal endothelial cells. (A, B) Immunofluorescent co-staining of rat liver cryosections with anti-ZO-1 (A, green), anti-ZO-2 (B, green), anti-VE-cadherin (A, B, red), and anti-Stabilin-2 (A, B, blue) antibodies. Images were acquired using laser scanning confocal microscopy. Bars 11.9 um.
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- Fig. 7. Decreased expression of proteins critical to ventral foregut morphogenesis in Foxa2loxP/loxP; Isl1-Cre embryos embryos. (A-D) Anti-Foxa2 and anti-ZO-1 (A-B) or anti-ZO-2 (C-D) coimmunohistochemistry (IHC) on Foxa2+/loxP (A, C) and Foxa2loxP/loxP; Isl1-Cre (B, D) embryos with 4-5 somite pairs (som). (A-B) Sections posterior to the anterior intestinal portal. (C-D) Sections through the foregut. White arrow in D marks a cluster of cells retaining expression of both Foxa2 and ZO-2. (E-F) Sections of anti-SOX17, anti-E-cadherin co-IHC near the anterior intestinal portal of Foxa2+/loxP (E) and Foxa2loxP/loxP; Isl1-Cre (F) embryos with 5 som. Segments of ventral foregut endoderm lacking Sox17 expression were observed in the mutant (white arrowheads). (G-H) Anti-Gata4, anti-E-cadherin (E-cad) co- IHC on sections of Foxa2loxP/loxP (G) and Foxa2loxP/loxP; Isl1-Cre (H) embryos with 5 somite pairs (som). Sections are posterior to the anterior intestinal portal. E-cadherin localizes to epithelial membranes and marks foregut endoderm. (I) Anti-Foxa2, anti-E-cadherin co-IHC on a section adjacent to that shown in B.
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- Figure 5 Notch signalling is not required for the acquisition of polarity and initial development of rosettes during neural differentiation. Immunohistochemistry for (A) Par3/CD133, (B) Zo-1/phosphorylated myosin light chain (PMLC), (C) N-cadherin/CD133 and (D) PKCzeta reveal that up until day 5, lumen/polarity stains are similar in CSL +/- and CSL -/- differentiations, and that CSL -/- differentiations display lumens at around day 5, similar to CSL +/- differentiations. The development of these lumens is quantified in (E), showing that indeed development is similar up to day 5 (N = 3). (F) CD133 qPCR follows a similar pattern over 6 days of differentiation, with an initially normal induction and subsequent loss of CD133 mRNA. Error bars show standard deviation. ***significant difference at p
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- Figure 7 rEhCP112a degrades claudin-1 and increases claudin-2 expression in Caco-2 cells. (A) Caco-2 cells incubated with rEhCP112a for different times or with live trophozoites (T) for 10 min, submitted to WB using antibodies against TJ proteins indicated at left and alpha-tubulin as a loading control. (B) Densitometry analysis of bands obtained in (A) for each TJs protein with regards to tubulin. * p
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- Figure 8 rEhCP112p binds to claudin-1 and claudin-2. Confluent Caco-2 cell monolayers were incubated for 10 min with rEhCP112p, then, cell lysates were immunoprecipitated (IP) in the presence of protease inhibitors, using alpha-EhCP112 antibody or pre-immune serum (PS). Immunoprecipitates, rEhCP112p and Caco-2 cell lysates (Caco-2) were submitted to WB assays and revealed using the antibodies indicated at left.
