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Protein structure
TJP2
Tight junction protein 2DFNA51, X104, ZO-2, ZO2
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Top validated antibodies |
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| Invitrogen Antibodies |  71-1400 |
84 references | Polyclonal |
WB
EL
ICC
IHC
OA
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| Proteintech Group | 18900-1-AP |
9 references | Polyclonal |
WB
EL
ICC
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| Novus Biologicals | NBP1-86850 |
4 references | Polyclonal |
WB
ICC
IHC
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| Atlas Antibodies | HPA001813 |
1 references | Polyclonal |
WB
ICC
IHC
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| Boster Biological Technology | A02774-1 |
Polyclonal |
WB
ICC
IHC
FC
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