MPP3

This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]

Description

Membrane palmitoylated protein 3

Tissue specificity

Group enriched (brain, heart muscle)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

17 (43800799 - 43833170)

Ensembl ID

ENSG00000161647  (ver. 103.38)

Orthologs

Mouse Mpp3: ENSMUSG00000052373

UniProt

Q13368

neXtProt

NX_Q13368

Human splice variants
Mouse splice variants

Protein structure