BS3490

antibody from Bioworld Technology, Inc
Targeting: IL12A CLMF, IL-12A, NFSK, NKSF1, p35
Provider product page for BS3490
Western blot
Immunohistochemistry

Antibody data

Product number
BS3490 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3490, RRID:AB_1661916
Product name
IL 12A (T65) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 32-81of Human IL-12A.
Description
IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-ÎÛ (IFN-ÎÛ). It also activates production of tumor necrosis factor Ï« (TNFÏ«) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-ÎÛ. IL-12 also has anti-angiogenic activity since the production of IFN-ÎÛ increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL12A protein structure - BS3490 shown in red.