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Protein structure
IGFBP3
Insulin like growth factor binding protein 3BP-53, IBP3
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  10189-2-AP |
17 references | Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | AF675 |
10 references | Polyclonal |
WB
IHC
BN
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| R&D Systems | AF675 |
9 references | Polyclonal |
WB
IHC
BN
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| antibodies-online | ABIN686497 |
1 references | Polyclonal |
WB
ICC
IHC
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| Bioss | bs-1434R |
1 references | Polyclonal |
WB
ICC
IHC
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