BS6738

antibody from Bioworld Technology, Inc
Targeting: SPARC BM-40, ON, ONT
Provider product page for BS6738
Western blot
Immunohistochemistry

Antibody data

Product number
BS6738 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SPARC polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SPARC.
Description
SPARC (for secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. It is identical to osteonectin, a protein important to bone calcification that is highly conserved between species. SPARC, which can be selectively expressed by the endothelium in response to certain types of injury, induces rounding in adherent endothelial cells in vitro. It regulates endothelial barrier function through F-Actin-dependent changes in cell shape, coincident with the appearance of intercellular gaps, which provide a paracellular pathway for extravasation of macromolecules.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SPARC protein structure - BS6738 shown in red.