Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14892-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14892-1-AP, RRID:AB_2160044
- Product name
- PCK2 antibody
- Antibody type
- Polyclonal
- Description
- PCK2 antibody (Cat. #14892-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bicyclol Regulates Hepatic Gluconeogenesis in Rats with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease by Inhibiting Inflammation.
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic Pathway Contributes to Oxidative and Lactic Injury After Stroke.
Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension.
Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1.
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
Li H, Xu Q, Xu C, Hu Y, Yu X, Zhao K, Li M, Li M, Xu J, Kuang H
Frontiers in pharmacology 2021;12:644129
Frontiers in pharmacology 2021;12:644129
Human umbilical cord-derived mesenchymal stem cell-exosomal miR-627-5p ameliorates non-alcoholic fatty liver disease by repressing FTO expression.
Cheng L, Yu P, Li F, Jiang X, Jiao X, Shen Y, Lai X
Human cell 2021 Nov;34(6):1697-1708
Human cell 2021 Nov;34(6):1697-1708
Phosphoenolpyruvate Carboxykinase (PCK) in the Brain Gluconeogenic Pathway Contributes to Oxidative and Lactic Injury After Stroke.
Geng X, Shen J, Li F, Yip J, Guan L, Rajah G, Peng C, DeGracia D, Ding Y
Molecular neurobiology 2021 May;58(5):2309-2321
Molecular neurobiology 2021 May;58(5):2309-2321
Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells.
Hu Y, Deng K, Pan M, Liu S, Li W, Huang J, Yao J, Zuo J
American journal of translational research 2020;12(7):3842-3857
American journal of translational research 2020;12(7):3842-3857
Polysaccharides from Armillariella tabescens mycelia ameliorate insulin resistance in type 2 diabetic mice.
Yang R, Li Y, Cai J, Ji J, Wang Y, Zhang W, Pan W, Chen Y
Food & function 2020 Nov 18;11(11):9675-9685
Food & function 2020 Nov 18;11(11):9675-9685
Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension.
Valuparampil Varghese M, James J, Eccles CA, Niihori M, Rafikova O, Rafikov R
Journal of clinical medicine 2020 Feb 6;9(2)
Journal of clinical medicine 2020 Feb 6;9(2)
Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1.
Wang S, Ai H, Liu L, Zhang X, Gao F, Zheng L, Yi J, Sun L, Yu C, Zhao H, Li Y
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E911-E924
American journal of physiology. Endocrinology and metabolism 2019 Nov 1;317(5):E911-E924
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Li Y, Wang L, Zhou L, Song Y, Ma S, Yu C, Zhao J, Xu C, Gao L
Molecular and cellular endocrinology 2017 May 5;446:70-80
Molecular and cellular endocrinology 2017 May 5;446:70-80
TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.
Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, Fei Y, Li C
Scientific reports 2016 Apr 25;6:24859
Scientific reports 2016 Apr 25;6:24859
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
Cai D, Jia Y, Song H, Sui S, Lu J, Jiang Z, Zhao R
PloS one 2014;9(8):e105504
PloS one 2014;9(8):e105504
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 14892-1-AP(PCK2 antibody) at dilution of 1:200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14892-1-AP(PCK2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PCK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PCK2. This antibody recognizes human,mouse,rat antigen. The PCK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.