BS7033

antibody from Bioworld Technology, Inc
Targeting: MASP1 CRARF, MASP, PRSS5
Provider product page for BS7033

Antibody data

Product number
BS7033 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MASP1 (HC) polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MASP1 heavy chain.
Description
MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MASP1 protein structure - BS7033 shown in red.