CABT-B10722

antibody from Creative Diagnostics

Targeting: MXD1 bHLHc58, MAD, MAD1

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B10722

Provider

Creative Diagnostics

Product name

Mouse anti-Human MXD1 monoclonal antibody, clone 3H20

Antibody type

Monoclonal

Description

This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3H20

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.