Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- sc-335 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-335, RRID:AB_2255249
- Product name
- Anti-SRF
- Antibody type
- Polyclonal (Antigen purified)
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Rabbit
Submitted references Transcription Mapping of Embryonic Rat Brain Reveals EGR-1 Induction in SOX2 Neural Progenitor Cells.
Elevated miR-499 Levels Blunt the Cardiac Stress Response.
The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signaling.
Chromatin remodeling complex NURF regulates thymocyte maturation.
Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells.
KLF3 regulates muscle-specific gene expression and synergizes with serum response factor on KLF binding sites.
Characterization of the human insulin-induced gene 2 (INSIG2) promoter: the role of Ets-binding motifs.
Significant correlation of species longevity with DNA double strand break recognition but not with telomere length.
The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin.
Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice.
Enhancer of polycomb1 acts on serum response factor to regulate skeletal muscle differentiation.
Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis.
Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy.
Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.
Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans.
Human T-cell leukemia virus type 1 Tax enhances serum response factor DNA binding and alters site selection.
Serum response factor binding sites differ in three human cell types.
Activation of the human T-cell leukemia virus type 1 long terminal repeat by the ternary complex factor Elk-1.
Defining the mammalian CArGome.
Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes.
Wells T, Rough K, Carter DA
Frontiers in molecular neuroscience 2011;4:6
Frontiers in molecular neuroscience 2011;4:6
Elevated miR-499 Levels Blunt the Cardiac Stress Response.
Shieh JT, Huang Y, Gilmore J, Srivastava D
PloS one 2011 May 9;6(5):e19481
PloS one 2011 May 9;6(5):e19481
The essential function for serum response factor in T-cell development reflects its specific coupling to extracellular signal-regulated kinase signaling.
Mylona A, Nicolas R, Maurice D, Sargent M, Tuil D, Daegelen D, Treisman R, Costello P
Molecular and cellular biology 2011 Jan;31(2):267-76
Molecular and cellular biology 2011 Jan;31(2):267-76
Chromatin remodeling complex NURF regulates thymocyte maturation.
Landry JW, Banerjee S, Taylor B, Aplan PD, Singer A, Wu C
Genes & development 2011 Feb 1;25(3):275-86
Genes & development 2011 Feb 1;25(3):275-86
Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells.
Pattabiraman PP, Rao PV
American journal of physiology. Cell physiology 2010 Mar;298(3):C749-63
American journal of physiology. Cell physiology 2010 Mar;298(3):C749-63
KLF3 regulates muscle-specific gene expression and synergizes with serum response factor on KLF binding sites.
Himeda CL, Ranish JA, Pearson RC, Crossley M, Hauschka SD
Molecular and cellular biology 2010 Jul;30(14):3430-43
Molecular and cellular biology 2010 Jul;30(14):3430-43
Characterization of the human insulin-induced gene 2 (INSIG2) promoter: the role of Ets-binding motifs.
Fernández-Alvarez A, Soledad Alvarez M, Cucarella C, Casado M
The Journal of biological chemistry 2010 Apr 16;285(16):11765-74
The Journal of biological chemistry 2010 Apr 16;285(16):11765-74
Significant correlation of species longevity with DNA double strand break recognition but not with telomere length.
Lorenzini A, Johnson FB, Oliver A, Tresini M, Smith JS, Hdeib M, Sell C, Cristofalo VJ, Stamato TD
Mechanisms of ageing and development 2009 Nov-Dec;130(11-12):784-92
Mechanisms of ageing and development 2009 Nov-Dec;130(11-12):784-92
The smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin.
Long X, Tharp DL, Georger MA, Slivano OJ, Lee MY, Wamhoff BR, Bowles DK, Miano JM
The Journal of biological chemistry 2009 Nov 27;284(48):33671-82
The Journal of biological chemistry 2009 Nov 27;284(48):33671-82
Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice.
Sun K, Battle MA, Misra RP, Duncan SA
Hepatology (Baltimore, Md.) 2009 May;49(5):1645-54
Hepatology (Baltimore, Md.) 2009 May;49(5):1645-54
Enhancer of polycomb1 acts on serum response factor to regulate skeletal muscle differentiation.
Kim JR, Kee HJ, Kim JY, Joung H, Nam KI, Eom GH, Choe N, Kim HS, Kim JC, Kook H, Seo SB, Kook H
The Journal of biological chemistry 2009 Jun 12;284(24):16308-16316
The Journal of biological chemistry 2009 Jun 12;284(24):16308-16316
Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis.
Scobie KN, Hall BJ, Wilke SA, Klemenhagen KC, Fujii-Kuriyama Y, Ghosh A, Hen R, Sahay A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Aug 5;29(31):9875-87
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 Aug 5;29(31):9875-87
Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy.
Lamon S, Wallace MA, Léger B, Russell AP
The Journal of physiology 2009 Apr 15;587(Pt 8):1795-803
The Journal of physiology 2009 Apr 15;587(Pt 8):1795-803
Glucocorticoid receptor-mediated expression of caldesmon regulates cell migration via the reorganization of the actin cytoskeleton.
Mayanagi T, Morita T, Hayashi K, Fukumoto K, Sobue K
The Journal of biological chemistry 2008 Nov 7;283(45):31183-96
The Journal of biological chemistry 2008 Nov 7;283(45):31183-96
Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans.
Rose AJ, Frøsig C, Kiens B, Wojtaszewski JF, Richter EA
The Journal of physiology 2007 Sep 1;583(Pt 2):785-95
The Journal of physiology 2007 Sep 1;583(Pt 2):785-95
Human T-cell leukemia virus type 1 Tax enhances serum response factor DNA binding and alters site selection.
Winter HY, Marriott SJ
Journal of virology 2007 Jun;81(11):6089-98
Journal of virology 2007 Jun;81(11):6089-98
Serum response factor binding sites differ in three human cell types.
Cooper SJ, Trinklein ND, Nguyen L, Myers RM
Genome research 2007 Feb;17(2):136-44
Genome research 2007 Feb;17(2):136-44
Activation of the human T-cell leukemia virus type 1 long terminal repeat by the ternary complex factor Elk-1.
Winter HY, Dayaram T, Marriott SJ
Journal of virology 2007 Dec;81(23):13075-81
Journal of virology 2007 Dec;81(23):13075-81
Defining the mammalian CArGome.
Sun Q, Chen G, Streb JW, Long X, Yang Y, Stoeckert CJ Jr, Miano JM
Genome research 2006 Feb;16(2):197-207
Genome research 2006 Feb;16(2):197-207
Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes.
Callis TE, Cao D, Wang DZ
Circulation research 2005 Nov 11;97(10):992-1000
Circulation research 2005 Nov 11;97(10):992-1000
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Supportive validation
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- Main image
- Experimental details
- Immunohistochemical staining of human lymph node shows strong nuclear positivity in reaction center cells and cells outside reaction centra.
- Validation comment
- Staining pattern consistent with experimental and/or bioinformatic data.