DPABH-21932

antibody from Creative Diagnostics

Targeting: LEF1 TCF10, TCF1ALPHA, TCF7L3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

DPABH-21932

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-21932, RRID:AB_2517497

Product name

Rabbit Anti-Human LEF1 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL