13999-1-AP

antibody from Proteintech Group

Targeting: OLIG2 BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

13999-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#13999-1-AP, RRID:AB_2157541

Product name

OLIG2 antibody

Antibody type

Polyclonal

Description

OLIG2 antibody (Cat. #13999-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

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Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.

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eLife 2021 Nov 23;10

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Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination.

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A five-m6A regulatory gene signature is a prognostic biomarker in lung adenocarcinoma patients.

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Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain.

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TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway.

Ruganzu JB, Zheng Q, Wu X, He Y, Peng X, Jin H, Zhou J, Ma R, Ji S, Ma Y, Qian Y, Wang Y, Yang W
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Melatonin pretreatment alleviates the long-term synaptic toxicity and dysmyelination induced by neonatal Sevoflurane exposure via MT1 receptor-mediated Wnt signaling modulation.

Liang L, Zeng T, Zhao Y, Lu R, Guo B, Xie R, Tang W, Zhang L, Mao Z, Yang X, Wu S, Wang Y, Zhang H
Journal of pineal research 2021 Dec;71(4):e12771

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Phospholipase D and phosphatidylinositol-4-phosphate 5-kinase 1 are involved in the regulation of oligodendrocyte morphological differentiation.

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ADAM10 suppresses demyelination and reduces seizure susceptibility in cuprizone-induced demyelination model.

Zhu X, Yao Y, Yang J, Zhang C, Li X, Zhang A, Liu X, Zhang C, Gan G
Free radical biology & medicine 2021 Aug 1;171:26-41

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Leptin Receptor Deficiency Protects Mice against Chronic Cerebral Hypoperfusion-Induced Neuroinflammation and White Matter Lesions.

Du Y, Song Y, Zhang X, Luo Y, Zou W, Zhang J, Fu J
Mediators of inflammation 2020;2020:7974537

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Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.

Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137

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Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease.

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Nature 2020 Sep;585(7825):397-403

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Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model.

Chen M, Yang LL, Hu ZW, Qin C, Zhou LQ, Duan YL, Bosco DB, Wu LJ, Zhan KB, Xu SB, Tian DS
Journal of neuroinflammation 2020 Nov 6;17(1):333

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Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.

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Neuron 2020 Jul 8;107(1):65-81.e9

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Requirements of LEFTY and Nodal overexpression for tumor cell survival under hypoxia in glioblastoma.

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Molecular carcinogenesis 2020 Dec;59(12):1409-1419

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Valproic Acid Enhances Reprogramming Efficiency and Neuronal Differentiation on Small Molecules Staged-Induction Neural Stem Cells: Suggested Role of mTOR Signaling.

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Myelin Damage in Diffuse Axonal Injury.

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Frontiers in neuroscience 2019;13:217

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Journal of cellular biochemistry 2019 Jan 28;

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Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections.

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Scientific reports 2016 May 13;6:25946

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Poly-L-ornithine promotes preferred differentiation of neural stem/progenitor cells via ERK signalling pathway.

Ge H, Tan L, Wu P, Yin Y, Liu X, Meng H, Cui G, Wu N, Lin J, Hu R, Feng H
Scientific reports 2015 Oct 27;5:15535

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Neuropeptide Y has a protective role during murine retrovirus-induced neurological disease.

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Journal of virology 2010 Nov;84(21):11076-88

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human brain tissue were subjected to SDS PAGE followed by western blot with 13999-1-AP(OLIG2 antibody) at dilution of 1:400

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using 13999-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human gliomas using 13999-1-AP(OLIG2 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human gliomas using 13999-1-AP(OLIG2 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue