abx015948

antibody from Abbexa

Targeting: OLIG2 BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx015948

Provider

Abbexa

Product name

Oligodendrocyte Transcription Factor 2 (OLIG2) Antibody

Antibody type

Monoclonal

Description

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain.The protein is an essential regulator of ventral neuroectodermal progenitor cell fate.The gene is involved in a chromosomal translocation t (14;21) (q11.2;q22) associated with T-cell acute lymphoblastic leukemia.Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.Tissue specificity: Expressed in the brain, in oligodendrocytes.Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas.Expression in glioblastomas highly variable.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.