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TBXT
T-box transcription factor TT
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018]
Top validated antibodies |
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| R&D Systems |  AF2085 |
56 references | Polyclonal |
WB
ICC
IHC
ChIP
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| Novus Biologicals | AF2085 |
67 references | Polyclonal |
WB
ICC
IHC
ChIP
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| antibodies-online | ABIN1098136 |
2 references | Monoclonal |
WB
EL
IHC
FC
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| Biorbyt | orb153384 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX60654 |
Monoclonal |
WB
EL
IHC
FC
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