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Protein structure
CTNND2
Catenin delta 2GT24, NPRAP
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Top validated antibodies |
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| Novus Biologicals |  H00001501-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN951062 |
5 references | Polyclonal |
WB
IHC
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| Abnova Corporation | H00001501-M01 |
1 references | Monoclonal |
WB
EL
|
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| LSBio | LS-C167134 |
Polyclonal |
WB
IHC
|
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| NovoPro Bioscience Inc. | 124444 |
Polyclonal |
WB
EL
IHC
|
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