TCF4

gene product
bHLHb19, E2-2, ITF2, SEF2-1B
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
388 antibodies from 34 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
1 antibody
Novus Biologicals
10 antibodies
GeneTex
4 antibodies
Abnova Corporation
5 antibodies
antibodies-online
122 antibodies
NSJ Bioreagents
3 antibodies
Invitrogen Antibodies
6 antibodies
Acris Antibodies GmbH
4 antibodies
NovoPro Bioscience Inc.
5 antibodies
Antibodies.com
2 antibodies
Bioworld Technology, Inc
2 antibodies
Biorbyt
37 antibodies
Affinity Biosciences
2 antibodies
LifeSpan BioSciences, Inc.
65 antibodies
Abgent
5 antibodies
OriGene
8 antibodies
Aviva Systems Biology
4 antibodies
Atlas Antibodies
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
17 antibodies
ProSci
4 antibodies
Creative Diagnostics
4 antibodies
United States Biological
49 antibodies
MyBioSource
6 antibodies
St John's Laboratory
3 antibodies
Abiocode, Inc.
1 antibody
Boster Biological Technology
1 antibody
Exalpha Biologicals, Inc.
1 antibody
Leading Biology
4 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
1 antibody
Everest Biotech
1 antibody
Abbexa
3 antibodies
GenWay
2 antibodies