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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- ELISA [1]
- Immunocytochemistry [1]
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- Product number
- H00006925-M03 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00006925-M03, RRID:AB_2199267
- Product name
- Mouse Monoclonal TCF4 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. TCF4 (1G4)
- Reactivity
- Human, Mouse, Rat, Rabbit, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Building a schizophrenia genetic network: transcription factor 4 regulates genes involved in neuronal development and schizophrenia risk.
Glycogen synthase kinase-3β inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A.
Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance.
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation.
Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.
Xia H, Jahr FM, Kim NK, Xie L, Shabalin AA, Bryois J, Sweet DH, Kronfol MM, Palasuberniam P, McRae M, Riley BP, Sullivan PF, van den Oord EJ, McClay JL
Human molecular genetics 2018 Sep 15;27(18):3246-3256
Human molecular genetics 2018 Sep 15;27(18):3246-3256
Glycogen synthase kinase-3β inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A.
Dohare P, Cheng B, Ahmed E, Yadala V, Singla P, Thomas S, Kayton R, Ungvari Z, Ballabh P
Neurobiology of disease 2018 Oct;118:22-39
Neurobiology of disease 2018 Oct;118:22-39
Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance.
Ruiz de Garibay G, Mateo F, Stradella A, Valdés-Mas R, Palomero L, Serra-Musach J, Puente DA, Díaz-Navarro A, Vargas-Parra G, Tornero E, Morilla I, Farré L, Martinez-Iniesta M, Herranz C, McCormack E, Vidal A, Petit A, Soler T, Lázaro C, Puente XS, Villanueva A, Pujana MA
Disease models & mechanisms 2018 May 18;11(5)
Disease models & mechanisms 2018 May 18;11(5)
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.
Luo C, Lim JH, Lee Y, Granter SR, Thomas A, Vazquez F, Widlund HR, Puigserver P
Nature 2016 Sep 15;537(7620):422-426
Nature 2016 Sep 15;537(7620):422-426
Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation.
Forrest MP, Waite AJ, Martin-Rendon E, Blake DJ
PloS one 2013;8(8):e73169
PloS one 2013;8(8):e73169
Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis.
Tanaka A, Itoh F, Nishiyama K, Takezawa T, Kurihara H, Itoh S, Kato M
Blood 2010 May 20;115(20):4138-47
Blood 2010 May 20;115(20):4138-47
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TCF4 Antibody (1G4) [H00006925-M03] - Analysis of TCF4 expression in K-562 (Cat # L009V1).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: TCF4 Antibody (1G4) [H00006925-M03] - Detection limit for recombinant GST tagged TCF4 is approximately 1ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: TCF4 Antibody (1G4) [H00006925-M03] - Analysis of monoclonal antibody to TCF4 on HeLa cell. Antibody concentration 10 ug/ml
