PAB3597

antibody from Abnova Corporation

Targeting: GJD2 CX36, GJA9

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB3597

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB3597, RRID:AB_1575219

Product name

GJD2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of GJD2.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Mutations in the calcium-binding motifs of CDH23 and the 35delG mutation in GJB2 cause hearing loss in one family.

de Brouwer AP, Pennings RJ, Roeters M, Van Hauwe P, Astuto LM, Hoefsloot LH, Huygen PL, van den Helm B, Deutman AF, Bork JM, Kimberling WJ, Cremers FP, Cremers CW, Kremer H
Human genetics 2003 Feb;112(2):156-63

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Structure, chromosomal localization, and brain expression of human Cx36 gene.

Belluardo N, Trovato-Salinaro A, Mudò G, Hurd YL, Condorelli DF
Journal of neuroscience research 1999 Sep 1;57(5):740-52

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

The GJD2 polyclonal antibody (Cat # PAB3597) is used in Western blot to detect GJD2 in placenta tissue lysate.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with GJD2 polyclonal antibody (Cat # PAB3597) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)