Tissue expression
Cell line expression
Protein structure
CAPN3
Calpain 3CANP3, LGMD2, LGMD2A, nCL-1, p94
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ![]() |
4 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
1 references | Polyclonal |
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OriGene | ![]() |
Polyclonal |
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