Tissue expression
Cell line expression
Protein structure
MAP2K7
Mitogen-activated protein kinase kinase 7Jnkk2, MKK7, PRKMK7
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Top validated antibodies |
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antibodies-online | ![]() |
3 references | Monoclonal |
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Acris Antibodies GmbH | ![]() |
Monoclonal |
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OriGene | ![]() |
Monoclonal |
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GeneTex | ![]() |
Monoclonal |
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Abnova Corporation | ![]() |
Monoclonal |
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