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Protein structure
KEAP1
Kelch like ECH associated protein 1INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN1098137 |
2 references | Monoclonal |
WB
EL
ICC
FC
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| GeneTex | GTX60660 |
1 references | Monoclonal |
WB
EL
ICC
FC
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| LSBio | LS-C169147 |
Monoclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-99434 |
1 references | Polyclonal |
WB
ICC
IHC
OA
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| Novus Biologicals | NBP2-03319 |
1 references | Monoclonal |
WB
ICC
IHC
FC
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