MS4A3

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Description

Membrane spanning 4-domains A3

Tissue specificity

Tissue enriched (bone marrow)

Subcell location

Golgi apparatus

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins

Chromosome

11 (60056587 - 60071115)

Ensembl ID

ENSG00000149516  (ver. 103.38)

Orthologs

Mouse Ms4a3: ENSMUSG00000024681

UniProt

Q96HJ5

neXtProt

NX_Q96HJ5

Human splice variants
Mouse splice variants

Protein structure