Tissue expression
Cell line expression
Protein structure
TARBP2
TARBP2 subunit of RISC loading complexTrbp
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
13 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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OriGene | ![]() |
Monoclonal |
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Acris Antibodies GmbH | ![]() |
Monoclonal |
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