Tissue expression
Cell line expression
Protein structure
MED17
Mediator complex subunit 17CRSP6, CRSP77, DRIP80, SRB4, TRAP80
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | H00009440-M01 | 2 references | Monoclonal |
WB
EL
ICC
IHC |
|
Abnova Corporation | H00009440-M01 | 2 references | Monoclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | PA5-40839 | 1 references | Polyclonal |
WB
IHC
ChIP
OA |
|
LSBio | LS-B6197 | Monoclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN564067 | 2 references | Monoclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider