Tissue expression
Cell line expression
Protein structure
LIG1
DNA ligase 1This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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Novus Biologicals | ![]() |
27 references | Monoclonal |
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Proteintech Group | ![]() |
6 references | Polyclonal |
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antibodies-online | ![]() |
Monoclonal |
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Acris Antibodies GmbH | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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