Tissue expression
Cell line expression
Protein structure
HTR3A
5-hydroxytryptamine receptor 3A5-HT3A, 5-HT3R, HTR3
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NB100-41382 | 4 references | Polyclonal |
WB
EL
IHC
FC |
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Proteintech Group | 10443-1-AP | 6 references | Polyclonal |
WB
EL
IHC
FC |
|
Invitrogen Antibodies | MA5-31770 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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antibodies-online | ABIN188554 | 3 references | Polyclonal |
WB
EL
ICC
IHC |
|
Everest Biotech | EB07328 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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