Tissue expression
Cell line expression
Protein structure
MRPL40
Mitochondrial ribosomal protein L40MRP-L22, NLVCF
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Atlas Antibodies | ![]() |
3 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
3 references | Polyclonal |
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Affinity Biosciences | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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