Tissue expression
Cell line expression
Protein structure
UVRAG
UV radiation resistance associatedVPS38
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NBP1-18885 | 2 references | Polyclonal |
WB
ICC
IP
IHC |
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antibodies-online | ABIN1449617 | 1 references | Polyclonal |
WB
EL
ICC
IP
IHC
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|
Proteintech Group | 19571-1-AP | 4 references | Polyclonal |
WB
EL
ICC
|
|
GeneTex | GTX16333 | Polyclonal |
WB
ICC
IHC
|
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Invitrogen Antibodies | A301-996A | Polyclonal |
WB
IP
IHC
OA |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider