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HFE
Homeostatic iron regulatorHFE1, HLA-H
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN395159 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | H00003077-M01 |
1 references | Monoclonal |
WB
EL
ICC
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| Novus Biologicals | H00003077-M01 |
1 references | Monoclonal |
WB
EL
ICC
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| LSBio | LS-C169421 |
Monoclonal |
WB
EL
ICC
IHC
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| GeneTex | GTX54085 |
Polyclonal |
WB
ICC
IHC
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