SDK2

The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]

Description

Sidekick cell adhesion molecule 2

Tissue specificity

Tissue enhanced (brain, cervix, testis)

Subcell location

Nucleoplasm

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

17 (73334384 - 73644445)

Ensembl ID

ENSG00000069188  (ver. 103.38)

Orthologs

Mouse Sdk2: ENSMUSG00000041592

UniProt

Q58EX2

neXtProt

NX_Q58EX2

Human splice variants
Mouse splice variants

Protein structure