Tissue expression
Cell line expression
Protein structure
SIRPB1
Signal regulatory protein beta 1CD172b, SIRP-BETA-1
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Top validated antibodies |
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Invitrogen Antibodies | PA5-98148 | Polyclonal |
WB
EL
ICC
IHC |
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Cusabio Biotech Co., Ltd | CSB-PA021335LA01HU | Polyclonal |
WB
EL
ICC
IHC |
||
Biorbyt | orb182927 | Polyclonal |
WB
EL
ICC
IHC |
||
Proteintech Group | 11811-1-AP | Polyclonal |
WB
EL
IHC
|
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LSBio | LS-C679465 | Polyclonal |
WB
EL
ICC
IHC |
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