Tissue expression
Cell line expression
Protein structure
PAICS
Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthaseADE2H1, AIRC, PAIS
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | ![]() |
7 references | Polyclonal |
|
|
GeneTex | ![]() |
2 references | Monoclonal |
|
|
antibodies-online | ![]() |
3 references | Polyclonal |
|
|
Atlas Antibodies | ![]() |
3 references | Polyclonal |
|
|
Novus Biologicals | ![]() |
1 references | Monoclonal |
|