SSR1

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Description

Signal sequence receptor subunit 1

Tissue specificity

Low tissue specificity

Subcell location

Endoplasmic reticulum

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (7268306 - 7347446)

Ensembl ID

ENSG00000124783  (ver. 103.38)

Orthologs

Mouse Ssr1: ENSMUSG00000021427

UniProt

P43307

neXtProt

NX_P43307

Human splice variants
Mouse splice variants

Protein structure