DNAJB12

DNAJB12 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]). [supplied by OMIM, Mar 2008]

Description

DnaJ heat shock protein family (Hsp40) member B12

Tissue specificity

Low tissue specificity

Subcell location

Nuclear membrane, Endoplasmic reticulum

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Transporters

Chromosome

10 (72332830 - 72355149)

Ensembl ID

ENSG00000148719  (ver. 103.38)

Orthologs

Mouse Dnajb12: ENSMUSG00000020109

UniProt

Q9NXW2

neXtProt

NX_Q9NXW2

Human splice variants
Mouse splice variants

Protein structure