Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
ARHGAP26
Rho GTPase activating protein 26GRAF, KIAA0621, OPHN1L, OPHN1L1
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
Top validated antibodies |
|||||
| Proteintech Group |  17747-1-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
|
|
| Novus Biologicals | NBP1-89732 |
2 references | Polyclonal |
WB
ICC
IHC
|
|
| Invitrogen Antibodies | 17747-1-AP |
Polyclonal |
WB
IP
IHC
OA
|
||
| Abnova Corporation | PAB3298 |
3 references | Polyclonal |
WB
IHC
|
|
| NovoPro Bioscience Inc. | 111154 |
Polyclonal |
WB
EL
IP
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider