Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
HHIP
Hedgehog interacting proteinFLJ20992, HIP
This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height. [provided by RefSeq, Feb 2011]
Top validated antibodies |
|||||
| antibodies-online |  ABIN396574 |
5 references | Monoclonal |
WB
EL
IP
IHC
|
|
| Novus Biologicals | H00064399-M01 |
3 references | Monoclonal |
WB
EL
IP
IHC
|
|
| Abnova Corporation | H00064399-M01 |
1 references | Monoclonal |
WB
EL
IP
IHC
|
|
| Invitrogen Antibodies | H00064399-M01 |
Monoclonal |
WB
EL
IP
IHC
OA
|
||
| GeneTex | GTX112584 |
1 references | Polyclonal |
WB
ICC
IHC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider