Tissue expression
Cell line expression
Protein structure
PSMB9
Proteasome 20S subunit beta 9beta1i, LMP2, PSMB6i, RING12
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
Top validated antibodies |
|||||
Invitrogen Antibodies | 14544-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
||
LSBio | LS-C331680 | Polyclonal |
WB
ICC
IHC
|
||
NSJ Bioreagents | RQ8149 | Polyclonal |
WB
EL
ICC
IHC
FC
|
||
Proteintech Group | 14544-1-AP | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
OriGene | TA504349 | Monoclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider